摘要
目的:探究桂枝茯苓丸治疗非增殖期糖尿病视网膜病变(NPDR)的临床效果及其对眼部功能的影响。方法:选取2017年9月-2018年9月在本院治疗的65例NPDR患者为观察对象,根据掷硬币法分为治疗组(n=33)与对照组(n=32),两组均给予降糖处理,基于此治疗组加服桂枝茯苓丸,疗程均为1个月,评估治疗前后两组眼部功能、中医证候积分等指标的变化。结果:治疗后,治疗组的视力平均值、眼底病变改善评分均显著高于对照组,视力提高有效率、眼底改善有效率及眼底荧光造影(FFA)有效率均显著高于对照组,差异均有统计学意义(P<0.05);治疗后,治疗组黄斑中心凹厚度和中医证候积分均显著低于对照组(P<0.05)。结论:桂枝茯苓丸治疗非增殖期糖尿病视网膜病变能更好地提高患者视力,改善其眼底病变情况的结局,且安全,故推荐使用。
Objective:To explore the clinical effect of Guizhi Fuling Pill on non-proliferative diabetic retinopathy(NPDR)and its effect on ocular function.Method:A total of 65 NPDR patients treated in our hospital from September 2017 to September 2018 were randomly divided into 33 cases of treatment group and32 cases of control group according to the coin toss,two groups were given hypoglycemic treatment,based on this,the treatment group was given Guizhi Fuling Pill for one month,the changes of the eye function and TCM syndrome score of two groups were evaluated before and after treatment.Result:After treatment,the average visual acuity and the score of improvement of fundus lesions in the treatment group were significantly higher than those in the control group,and the visual acuity improvement efficiency,fundus improvement efficiency and Fundus fluorescein angiography(FFA)efficiency were significantly higher than those in the control group(P<0.05).After treatment,the macular fovea thickness and the score of TCM syndromes in the treatment group were significantly lower than those in the control group(P<0.05).Conclusion:Guizhi Fuling Pill can improve the visual acuity of patients with non-proliferative diabetic retinopathy and improve the outcome of their fundus lesions,it is safe,therefore,it is recommended to use Guizhi Fuling Pill in the treatment of non-proliferative diabetic retinopathy.
作者
王映璇
朱中贵
WANG Yingxuan;ZHU Zhonggui(Kangmei Hospital,Puning 515300,China)
出处
《中国医学创新》
CAS
2019年第6期73-76,共4页
Medical Innovation of China
基金
广东省揭阳市卫生和计划生育局医学科学技术研究项目(2018[177])
关键词
非增殖期
糖尿病视网膜病变
桂枝茯苓丸
视力
眼底病变
Non-proliferative
Diabetic retinopathy
Guizhi Fuling Pill
Visual acuity
Fundus lesions
