摘要
目的:建立传统性状评价和现代内在质量评价相结合的姜厚朴饮片等级评价标准。方法:测定28批姜厚朴饮片的外观性状参数和内在药效指标成分(厚朴酚与和厚朴酚)含量,计算相对质量常数,假设所测样品的平均相对质量常数为100%,其120%以上列为一等,60%~120%列为二等,剩余列为三等。结果:姜厚朴饮片的相对质量常数范围为0. 09~1. 78。一级姜厚朴饮片相对质量常数≥0. 64,二级姜厚朴饮片相对质量常数介于0. 32~0. 64,三级姜厚朴饮片相对质量常数≤0. 32。结论:相对质量常数结合了传统外在性状指标和内在药效成分指标,能够客观、合理、科学的划分姜厚朴饮片等级,可为建立和完善该饮片的等级标准提供参考。
Objective:To establish the grade evaluation standard for Magnoliae Officinalis Cortex processed with ginger juice by combining traditional morphology evaluation with modern intrinsic quality evaluation.Method:The morphological parameters and contents of intrinsic pharmacodynamic index components of 28 batches of Magnoliae Officinalis Cortex processed with ginger juice were determined,and the relative quality constants were calculated.Assuming that the average relative quality constant was 100%,more than 120%of the samples were classified as the first grade,60%to 120%as the second grade,the remaining as the third grade.Result:The relative quality constant of Magnoliae Officinalis Cortex processed with ginger juice ranged from 0.09 to 1.78.The relative quality constant of the first grade was≥0.64,the second grade was 0.32-0.64,while the third grade was≤0.32.Conclusion:Relative quality constant combines external indexes of traditional morphology and internal indexes of pharmacodynamic components,which can objectively,reasonably and scientifically classify the grade of Magnoliae Officinalis Cortex processed with ginger juice,and provide reference for establishing and improving the grade evaluation standard of this decoction pieces.
作者
张权
荆文光
邓哲
杜杰
兰青山
ZHANG Quan;JING Wen-guang;DENG Zhe;DU Jie;LAN Qing-shan(China National Traditional Chinese Medicine Co.Ltd.,Beijing 102600,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100193,China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2019年第22期115-120,共6页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家中药标准化项目(ZYBZH-Y-ZY-45)
关键词
姜厚朴
饮片
相对质量常数
等级评价
厚朴酚
和厚朴酚
外观性状
Magnoliae Officinalis Cortex processed with ginger juice
decoction pieces
relative quality constant
grades evaluation
magnolol
honokiol
appearance
