摘要
目的 探讨美国重症肌无力协会 (MGFA)临床分型及定量评分 (QMG)的临床特点及意义。方法 对 2 0 0 1年 1 1月～ 2 0 0 3年 9月手术治疗的 4 3例重症肌无力病人 ,以MGFA标准作临床分型与定量评分 ,通过与Osserman分型作比较 ,观察手术治疗前后的变化 ,分析并探讨新的分型与评分的临床特点与意义。结果 MGFA临床分型中的Ⅰ型与OssermanⅠ型较一致 ,Os sermanⅡa型 1 7例中 ,MGFAⅡa型 1 2例 ,Ⅲa型 4例 ,Ⅲb型 1例 ;OssermanⅡb型 1 5例中 ,MGFAⅡa型 2例 ,Ⅱb型 4例 ,Ⅲa型3例 ,Ⅲb型 3例 ,Ⅳa型 2例 ,Ⅳb型 1例 ;治疗后QMG评分随时间呈明显降低。结论 美国重症肌无力协会临床分型较Osser man分型更为细致、客观 ,其定量评分准确反映出治疗前后病情的变化 ,值得在临床上推广应用 ,以加强对重症肌无力的临床研究与协作。
Objective To explore the clinical singnificance of the new classification and quantitive MG (QMG) score published by MGFA (Myasthenia Gravis Foundation of America).Metheods From Nov.2001 to Sep.2003,43 MG patients were classified both with Osserman classification and MGFA clinical classification,which differences between the two classifications were analized.The QMG score was also studied before and after thymectomy.Results MGFA typeⅠhad the same meaning with Osserman typeⅠ,and the patients,which were used to be Osserman typeⅡa to type Ⅳ,were classified into 6 types from MGFA typeⅡa to Ⅳb,according to QMG examination.The QMG score was changed with thymectomy and the time of follow up.Conclusion MGFA clinical classification associated with QMG examination was more objective and precise than Osserman classification,and the individual QMG score was accordant with and reflected the outcome after thymectomy.Both MGFA clinical classification and QMG should be widely used in clinical works for deeping the study.
出处
《重庆医学》
CAS
CSCD
2004年第2期165-168,共4页
Chongqing medicine
关键词
重症肌无力
临床分型
评分
myasthenia gravis(MG)
clinical classification
score
