摘要
目的探讨腹股沟斜疝患儿血清中MMP-2、TIMP-2、TIMP-1含量同小儿腹股沟斜疝发病的相关性。方法以在该院行腹股沟斜疝修补术的患儿为研究对象,非疝患儿为对照组,收集二组患者血清标本,对血清MMP-2、TIMP-2、TIMP-1含量进行检测。结果腹股沟斜疝患儿血清MMP-2水平与对照组相比差异无统计学意义(P>0.05);血清TIMP-2水平与对照组相比差异无统计学意义(P>0.05);血清TIMP-1水平与对照组相比差异无统计学意义(P>0.05)。结论和胶原蛋白代谢密切相关的血清MMP-2、TIMP-2、TIMP-1没有参与小儿腹股沟斜疝的发病。
Objective To explore the correlation of serum MMP-2,TIMP-2 and TIMP-1 content with the incidence in children with inguinal hernia.Methods The children with inguinal hernia repair were selected as the study subjects in author's hospital;non-hernia in children were in the control group.Serum samples were collected for the two groups of patients,and serum MMP-2,TIMP-2,TIMP-1 content were detected.Results Serum levels of MMP-2,TIMP-1,TIMP-2 in inguinal hernia was no significant difference(P>0.05)compared to the control group.Conclusion Serum MMP-2 and TIMP-2 and TIMP-1 content,closely related to collagen metabolism,is not involved in the pathogenesis of pediatric inguinal hernia.
出处
《中国煤炭工业医学杂志》
2017年第3期260-262,共3页
Chinese Journal of Coal Industry Medicine
