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Schlafen基因家族及与肿瘤相关的研究进展 被引量:2

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摘要 Schlafen(Slfn)基因家族是1988年由Schwarz等〔1〕发现的参与调控人与鼠等众多生物学功能的一类重要基因。最早发现的Slfns家族基因是4个鼠源基因(鼠源Slfn 1、2、3、4),分别表达在T细胞活化和胸腺细胞成熟过程中的不同时期。研究证实Slfns家族基因从细菌、病毒到鼠、马、人等分布各个物种,具有较广泛的同源性。研究表明Slfn蛋白可以抑制细胞增殖、
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第22期6613-6615,共3页 Chinese Journal of Gerontology
基金 国家自然科学基金青年科学基金(No.81102013) 浙江省杰出青年基金(No.R2090353)
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  • 1Gabriele Zoppoli,Marie Regairaz,Elisabetta Leo,William C. Reinhold,Sudhir Varma,Alberto Ballestrero,James H. Doroshow,Yves Pommier.Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents[J]. Proceedings of the National Academy of Sciences . 2012 (37) 被引量:1
  • 2Vaishali B. Patel,Yingjie Yu,Jayanta K. Das,Bhaumik B. Patel,Adhip P.N. Majumdar.Schlafen-3: A novel regulator of intestinal differentiation[J]. Biochemical and Biophysical Research Communications . 2009 (4) 被引量:1
  • 3Olivia Bustos,Saijal Naik,Gayle Ayers,Claudio Casola,Maria A. Perez-Lamigueiro,Paul T. Chippindale,Ellen J. Pritham,Elena de la Casa-Esperón.Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence[J]. Gene . 2009 (1) 被引量:1
  • 4Brent Neumann,Liang Zhao,Kathleen Murphy,Thomas J. Gonda.Subcellular localization of the Schlafen protein family[J]. Biochemical and Biophysical Research Communications . 2008 (1) 被引量:1
  • 5Na Kyung Lee,Han Kyung Choi,Hyun Joo Yoo,Jihye Shin,Soo Young Lee.RANKL-induced schlafen2 is a positive regulator of osteoclastogenesis[J]. Cellular Signalling . 2008 (12) 被引量:1
  • 6Liang Zhao,Brent Neumann,Kathleen Murphy,John Silke,Thomas J. Gonda.Lack of reproducible growth inhibition by Schlafen1 and Schlafen2 in vitro[J]. Blood Cells, Molecules and Diseases . 2008 (2) 被引量:1
  • 7Wern-Joo Sohn,Dongbum Kim,Keun-Wook Lee,Min-Soo Kim,Sanghoon Kwon,Younghee Lee,Doo-Sik Kim,Hyung-Joo Kwon.Novel transcriptional regulation of the schlafen-2 gene in macrophages in response to TLR-triggered stimulation[J]. Molecular Immunology . 2007 (13) 被引量:1
  • 8The dynamics of the LPS triggered inflammatory response of murine microglia under different culture and in vivo conditions[J]. Journal of Neuroimmunology . 2006 (1) 被引量:1
  • 9David A Schwarz,Carol D Katayama,Stephen M Hedrick.Schlafen , a New Family of Growth Regulatory Genes that Affect Thymocyte Development[J]. Immunity . 1998 (5) 被引量:1
  • 10Renard J P,Babinet C.Identification of a paternal developmental effect on the cytoplasm of one-cell-stage mouse embryos. Proceedings of the National Academy of Sciences of the United States of America . 1986 被引量:1

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