摘要
微粒皮移植术自应用临床以来,已经成功治疗了大量严重烧伤患者,并逐渐成为大面积深度烧伤患者主要的创面修复方式之一。但是,微粒皮移植术仍然存在很多的问题,如I期愈合率相对较低,创面愈合后反复破溃,后期瘢痕增生较严重等。本文就近年来国内外学者对微粒皮移植的大量基础研究和临床观察进行了总结,重点阐述了异体微粒皮、真皮基质以及干细胞在微粒皮移植中的应用。这些方法对深度烧伤的创面愈合速度及愈后质量均有显著提高。
Since the microskin grafting was clinically applied in burn wound management,it has successfully cured a large number of patients with severe burns and gradually become one of the most wound repairing techniques for patients with extensive burn wounds. However,there are still quite a few problems in clinical practice of microskin grafting,such as the lower rate of primary wound healing,repeated ulceration and obvious scarring in healed wound. This review summarizes the current progress in the basic researches and clinical experiences of microskin graft,focuses on the mixed grafting of autologous and allogeneic microskin,and the composite microskin grafting with dermal matrix,and the application of stem cell in microskin grafting. These novel techniques could significantly improve the rate and quality of wound healing in the repairment of severe deep burn wounds.
出处
《中华损伤与修复杂志（电子版）》
CAS
2016年第4期310-313,共4页
Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
基金
国家公益性卫生行业科研专项(201202002)
