摘要
目的了解乌鲁木齐市耐药肺结核患者地区分布。方法将2011年5月1日至2012年9月30日间,乌鲁木齐市七区一县疾控中心结核病防治科收治的肺结核患者标本用罗氏管进行分枝杆菌分离培养鉴定,培养阳性菌株采用比例法对8种抗结核药物:异烟肼、链霉素、乙胺丁醇、利福平、氧氟沙星、卡那霉素、阿米卡星、卷曲霉素进行药物敏感性试验。并对其耐药情况进行统计分析。结果 259例肺结核患者做药敏试验,其中本地患者182例,外地患者77例,总耐药率分别为29.7%和22.1%,一线抗结核药物的耐药率分别为25.8%和15.6%。市辖七区一县耐药率在20%-40%之间,耐多药率在0-10%之间。结论本地外地及所辖区县的耐药率耐多药率差别均无统计学意义(P】0.05)。异烟肼耐药率低于全国耐药水平。
0bjective Understanding the geographical distribution of patients with drug resistant tuberculosis in Urumqi.Methods Tuberculosis of Seven areas one county CDC in Urumqi of 2011.5.1-2012.9.30,specimens were cultured with L-J medium,culture positive isolates using the Drug sensitive test of 8 anti-tuberculosis drugs:INH、RFP、EMB、SM、OFX、KM、AK and CPM.And make statistical analysis of the drug resistance.Results 259 cases of pulmonary tuberculosis patient with Drug sensitive test.Local patients with 182 cases,77 cases of foreign patients.Total drug resistance rate were 29.7% and 22.1%.The first-line anti-TB drug resistance rates were 25.8% and 15.6%,respectively.Seven districts and one county resistance rates between 20%-40%,multi-drug resistant rate between 0-10%.Conclusions Resistance rate of the local 、field and Seven districts and one county rates of multidrug-resistant difference was not statistically significant(P > 0.05).The level of isoniazid resistance rate lower than the national level of resistance.
出处
《中国保健营养（下半月）》
2012年第11期5363-5364,共2页
China Health Care & Nutrition
关键词
结核分枝杆菌
痰涂片
痰培养
药敏试验
Mycobacterium tuberculosis
Sputum smear
Sputum culture
Drug sensitive test
