摘要
目的分析我所183株痰培养阳性菌株的耐药情况。方法采用药敏比例法对183株阳性菌株进行菌种鉴定及药物敏感性试验。结果共分离出174株结核分枝杆菌,且4种一线抗结核药物异烟肼(INH)、利福平(RFP)、乙胺丁醇(EMB)、链霉素(SM)的总耐药率为25.3%,耐多药率为8.0%。4种抗结核药物的耐药率由高到低依次为SM、INH、EMB、RFP。结论陕西省结核耐药情况仍较严重。
Objective To analyze the status of drug resistance in 183 cases of the sputum culture-positive strains isolated in our institute. Methods The proportional method was used in bacteria identification and drug sensitivity tests of 183 strains. Results 174 strains of Mycobacterium tuberculosis were isolated,and the total drug resistance rate to 4 first-line anti tuberculosis drugs（ INH,RFP,EMB,SM） was 25. 3% and their multi drug resistant rate was 8. 0%. It showed the highest resistance to SM,followed by INH,EMB and RFP. Conclusion The drug resistance of Mycobacterium tuberculosis in Shanxi province is still serious.
出处
《临床肺科杂志》
2014年第8期1460-1462,共3页
Journal of Clinical Pulmonary Medicine
关键词
结核分枝杆菌
药物敏感试验
耐药结核病
Mycobacterium tuberculosis
drug-susceptibility testing
drug-resistant tuberculosis
