摘要
氧化应激被认为是衰老和疾病的重要原因,因此对抗氧化应激损伤的研究广泛而深入。植物雌激素种类繁多、不良反应较小,具有合成雌激素不可替代的优点。本文按照植物雌激素的化学结构进行分类,阐述了其在抗氧化应激损伤方面的实验研究进展,为深入研究植物雌激素的作用机制和分子路径提供依据,为临床治疗提供理论基础。
Oxidative stress is considered to be an important cause of aging and multiple diseases,studies associated with antioxidative stress have drawn extensive and intensive attention. Phytoestrogens have high varieties and few side effects compared with synthetic estrogens. This paper reviewed phytoestrogens according to the chemical structure and the experimental research progress in antioxidative stress injury,providing a basis for further research on the mechanisms and molecular pathways of them and expounding a theoretical basis for clinical treatment.
作者
陈梦
刘欣
吴丹
石丹宁
孙丽萍
赵丕文
Chen Meng;Liu Xin;Wu Dan;Shi Danning;Sun Liping;Zhao Piwen(School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 102488,China;School of Life Sciences,Beijing University of Chinese Medicine,Beijing 102488,China;Department of Emergency,Third Affiliated Hospital,Beijing University of Chinese Medicine,Beijing 100029,China)
出处
《中国医药》
2019年第3期463-466,共4页
China Medicine
基金
国家自然科学基金(81673764)
北京中医药大学青年教师项目中央高校基本科研业务费专项资金资助(2017-JYB-JS-001)~~
关键词
植物雌激素
氧化应激
活性氧自由基
超氧化物歧化酶
丙二醛
Phytoestrogens
Oxidative stress
Reactive oxygen species
Superoxide dismutase
Malondialdehyde
