摘要
目的探讨急性酒精中毒对失血性休克后早期血气分析的影响。方法随机将40只健康新西兰大耳白兔均分为4组,分别为对照组(A组)、失血性休克组(B组)、急性酒精中毒组(C组)和急性酒精中毒合并失血性休克组(D组),比较四组达到休克所需的放血量和恢复伤前血压的补血补液总量,休克前、休克中、休克复苏后1 h和休克复苏后3 h测定动脉血血气分析情况。结果 D组的放血量小于B组,复苏需要更多液体;与A组比较,休克中与复苏后B组、C组及D组p H、Pa O2下降,Pa CO2、乳酸值升高;与B组比较,D组血清p H,Pa O2下降,Pa CO2乳酸升高更明显。B、C、D组p H值、Pa CO2、Pa O2、乳酸值不同时点和组间Pa O2比较,差异具有统计学意义;三组间不同时间p H值、Pa CO2、Pa O2、乳酸值无交互作用。结论失血性休克后会产生酸中毒,氧分压下降,急性酒精中毒能加重这种变化。
Objective To study the effects of acute alcoholism on blood gas analysis in rabbits. Methods Forty New Zelanian big-ear rabbits were divided into four groups randomly. The control group(Group A), the hemorrhagic shock group(Group B), the acute alcoholism group(Group C)and the acute alcoholism and hemorrhagic shock combination group(Group D). Results The volume of blood of Group D was less than Group B. The volume of lipid of Group D needed more. pH and Pa O2 of Group D and Group B were decreased than Group A, Pa CO2 and lactic acid were risen in the shock and recovered. pH and Pa O2 of D Group were decreased than B Group, Pa CO2 and lactic acid of D Group were risen than Group B. pH, Pa O2, Pa CO2 and lactic acid for different time and different group weren't statistically significant. There was no interaction of pH, Pa O2, Pa CO2 and lactic acid in different time and different group.Conclusion It will achieved acidosis and decrease in partial pressure of oxygen after hemorrhagic shock. Acute alcoholism can aggravate them.
出处
《中国现代医生》
2014年第35期8-10,共3页
China Modern Doctor
基金
江西省科技厅科技计划(2009BSB11213)
江西省卫生厅科技计划(20091036)
关键词
急性酒精中毒
失血性休克
血气分析
Acute alcoholism
Hemorrhagic shock
Blood gas analysis
