摘要
目的探讨长期家庭氧疗(LTDOT)对缓解期慢性阻塞性肺疾病(COPD)患者的疗效。方法选取治疗出院的缓解期COPD患者56例,随机分为观察组和对照组,各28例。观察组在常规治疗的基础上给予LTDOT,每日吸氧15 h以上,氧流量1~2 L/min,治疗持续18个月;对照组则未进行家庭氧疗。测定两组患者治疗前后的肺功能中第一秒用力呼气容积占预计值百分比(FEV1%预计值)、血气分析指标动脉血氧分压(Pa O2)和二氧化碳分压(Pa CO2)。采用SPSS 18.0统计软件进行统计分析,计量资料用均数±标准差(xˉ±s)表示,治疗前后比较采用配对t检验,组间比较采用方差分析。计数资料用率(%)表示,采用χ2检验,P<0.05表示差异有统计学意义。结果观察组Pa O2水平、FEV1占预计值均高于对照组,差异有统计学意义(P<0.01)。结论 LTDOT能有效改善缓解期COPD患者的肺功能和Pa O2水平。
Objective To observe the effects of long-term domiciliary oxygen therapy on chronic obstructive pulmonary diseases(COPD) patients. Methods Fifty-six patients diagnosed with COPD were divided into the observation group and the control group. Based on the regular treatment, patients in the observation group received domestic oxygen treatment over 15 hours a day. After 18 months, the blood gas analysis(Pa O2, Pa CO2) and pulmonary functions(FEV1) of the patients were analyzed and compared. Results The levels of Pa O2 and FEV1 of the patients in the observation group were higher than those in the control group with significant difference(P<0.01). Conclusions Long-term domestic oxygen treatment may effectively improve Pa O2 and pulmonary functions of patients with COPD.
出处
《慢性病学杂志》
2016年第3期305-306,309,共3页
Chronic Pathematology Journal
关键词
慢性阻塞性肺疾病
长期家庭氧疗
肺功能
Chronic obstructive pulmonary disease
Long-term domiciliary oxygen therapy
Pulmonary function
