摘要
目的:探讨尤瑞克林对急性脑梗死患者神经功能的改善作用。方法:选取我院急性脑梗死患者250例,采用随机数字表法将患者分为观察组与对照组,各125例。对照组采用常规治疗,观察组在对照组基础上加用尤瑞克林治疗,比较2组临床疗效、NIHSS评分与脑梗死病灶体积的差异。结果:观察组治疗总有效率明显高于对照组(P<0.05)。治疗前,2组患者NIHSS评分与脑梗死病灶体积比较无显著性差异(P>0.05);治疗后,全部患者NIHSS评分与脑梗死病灶体积均明显低于治疗前(P<0.05),观察组患者NIHSS评分与脑梗死病灶体积均明显低于对照组患者(P<0.05)。结论:尤瑞克林治疗急性脑梗死患者的临床疗效显著,且通过降低脑梗死病灶体积,从而显著改善神经功能,值得临床推广应用。
Objective: To investigate the effect of urinary kallidinogenase on neurological function improvement in patients with acute cerebral infarction. Methods: 250 cases of patients with acute cerebral infarction in our hospital were divided into observation group and control group by using random number table,125 cases in each group; the control group were treated with routine therapy,while observation group were given not only routine therapy but also urinary kallidinogenase treatment. The clinical curative effect,NIHSS score and cerebral infarction volume were compared between the two groups. Results: The total effective rate of observation group was significantly higher than that of the control group( P < 0. 05). Before treatment,there were no significant differences in NIHSS score and cerebral infarction volume between the two groups( P > 0. 05); NIHSS score and cerebral infarction volume after treatment in all patients were significantly lower than those before treatment( P < 0. 05). In addition,the above two indicators in the observation group were significantly lower than those in the control group after treatment( P < 0. 05). Conclusion: Urinary kallidinogenase has significant curative effect in the treatment of acute cerebral infarction. By reducing the cerebral infarction volume,it can significantly improve the neurological function and is worthy of clinical application.
出处
《现代临床医学》
2016年第3期180-181,184,共3页
Journal of Modern Clinical Medicine
基金
惠州市科技计划项目(血管内介入治疗联合rt-PA静脉溶栓及尤瑞克林治疗急性脑梗死的研究)
编号2015Y006
关键词
尤瑞克林
急性脑梗死
神经功能
urinary kallidinogenase
acute cerebral infarction
neurological function
