摘要
目的了解南宁市男男性行为人群(men who have sex with men,MSM)人类免疫缺陷病毒(HIV)新发感染情况及感染危险因素。方法对南宁市2013-2015年连续4轮MSM人群2 524名进行横断面调查,并采集3～5 ml静脉血进行HIV抗体和梅毒检测。应用BED捕获酶联免疫法(BED-CEIA)对HIV抗体确证阳性样本进行HIV-1新发感染检测,估算HIV-1新发感染率,对调查资料进行χ2检验和Logistic回归分析。结果 4轮调查中HIV阳性率分别为6. 98%、11. 65%、11. 98%、11. 40%,新发感染率分别为2. 48%、6. 34%、7. 10%、7. 64%。多因素Logistic回归分析提示本地居住时间(OR=0. 583～0. 897),艾滋病防治知晓率(OR=0. 336～0. 978),性角色(OR=1. 334～1. 710),最近6个月与同性肛交使用安全套频率(OR=0. 501～0. 750),现症梅毒感染(OR=2. 561～4. 091)是HIV感染的危险因素。结论南宁市MSM人群HIV感染率处于较高水平,新发感染率有上升趋势。应该加强主动监测,加大干预力度。
Objective To undrestand recent HIV infection and associated factors among men who have sex with men in Nanning City. Methods A cross-sectional survey of 2 524 consecutive MSM populations in Nanning from 2013 to 2015 was conducted,and 3 to 5 ml of venous blood was collected for HIV antibody and syphilis testing. BED-enzyme-linked immunosorbent assay( BED-CEIA) was used to detect HIV-1 new infections in HIV-positive positive samples,and the new HIV-1 infection rate was estimated. The survey data were analyzed by χ2 test and logistic regression analysis. Results For the four rounds investigation,the HIV positive rates were 6. 98%,11. 65%,11. 98% and 11. 40% respectively and recent infection rates were2. 48%,6. 34%,7. 10%,7. 64% respectively during 2013-2015. The result of Logistic regression analysis showed that local residence time( OR = 0. 583 ~ 0. 897),HIV/AIDS knowledge awareness( OR = 0. 336 ~ 0. 978),sex role( OR = 1. 334 ~1. 710),nearly 6 months each sex were using condoms( OR = 0. 501 ~ 0. 750) and concurrent syphilis infection( OR = 2. 561 ~4. 091) were factors associated with HIV infection. Conclusion The HIV-1 infection rate among MSM was at a high level in Nanning,and the recent HIV-1 infection rate was upward trend. It is necessary to strengthen the active monitoring,and increase the intensity of intervention.
作者
潘海西
黄秋芳
刘海燕
栾苑
梁雪坚
PAN Haixi;HUANG Qiufang;LIU Haiyan;LUAN Yuan;LIANG Xuejian(Nanning City Center for Disease Control and Prevention,Guangxi530023,China)
出处
《医学动物防制》
2019年第3期226-229,共4页
Journal of Medical Pest Control
基金
"十二五"国家科技重大专项-中国疾病预防控制中心性艾中心关于开展男男性行为人群艾滋病新发感染评估项目(中疾控艾发[2012]109号)
关键词
男男性行为人群
艾滋病病毒
新发感染
危险因素
Men who have sex with men
Human immunodeficiency virus
Recent infection
Risk factor
