摘要
目的:分析我院皮肤药物反应的药品种类及其发生的相关因素,促进临床早诊断和及时处理。方法:对我院2015～2017年收集的352例药物致皮肤不良反应病例报告的类型、患者年龄分布、临床表现及涉及药物、严重不良反应情况等进行统计分析。结果:352例皮肤不良反应病例涉及的药物共有130种,其中抗菌药物居首位,给药途径以静脉滴注为主。一般的不良反应294例,严重的不良反应47例,新的不良反应11例。结论:临床医生应关注严重皮肤药物反应表现与危险因素,减少药源性不良反应的发生。
Objective: To analyze the drug-related factors about the occurrence of drug reactions in the skin,and promote early diagnosis and timely treatment in our hospital. Methods: The types,age distribution,clinical manifestations,drug involved and severe adverse reactions of 352 cases of skin adverse reactions in our hospital from 2015 to 2017 were analyzed. Results: 352 cases of drug-induced adverse skin reactions involving a total of 130 kinds of drugs,including antibiotics in the first place,the main route of administration by intravenous infusion,which contains 294 cases of general adverse reactions,47 cases of serious adverse reactions,and 11 cases of new adverse reactions. Conclusion: Clinicians should pay attention to the manifestations and risk factors of severe skin drug reactions,to reduce the occurrence of drug-induced adverse reactions.
作者
郑磊
徐洪玉
管玉瑶
杨静
宋超
Zheng Lei;Xu Hongyu;Guan Yuyao;Yang Jing;Song Chao(Shandong Provincial Third Hospital,Jinan 250031,China)
出处
《药物流行病学杂志》
CAS
2019年第2期122-125,共4页
Chinese Journal of Pharmacoepidemiology
基金
山东省医药卫生科技发展计划项目(编号:2017WS473)
山东省中医药科技发展计划项目(编号:2017-284)
