摘要
本文应用SOS显色试验研究了30种常用蔬菜提取物对N-甲基-N′-硝基-N-亚硝胍、苯并[a]芘和紫外线诱发的大肠杆菌SOS反应的抑制作用。结果表明,大部分蔬菜的丙酮提取物具有抑制SOS反应作用,部分蔬菜的水溶性提取物具有抑制SOS反应作用,抑制不同致突变物引起的SOS反应具有专一性。韭黄、大蒜叶、蒜瓣水溶性提取物是典型的SOS反应强抑制物。SOS显色试验结果与Ames试验结果一致。
In the present study, the SOS Chromotest has been used to screen vegetables inhibiting SOS responses induced by MNNG, B (α ) P, UV in E. coli. 30 common vegetables were screened. The results showed that acetone extracts of most vegetables reveal inhibitory effects on SOS responses,aqueous extracts of some vegetables alos reveal inhibitory effects on SOS responses, and they can specifically inhibit SOS responses induced by various mutagens . Aqueous extracts of hotbed chives, garlic leaves, fragrant flowered garlic, garlic cloves are typical strong inhibitory substances on SOS responses. The results obtained in the SOS Chromotest are the same as the results in Ames test.
出处
《卫生毒理学杂志》
CSCD
1992年第1期14-16,共3页
Journal of Health Toxicology
关键词
蔬菜
致突变物
SOS反应
vegetables
mutagens
SOS responses
SOS Chromotest
antimutagenic effects
