摘要
抗菌药物在淋病的防治中发挥了重要作用,但随着抗菌药物耐药现象的不断出现和耐药菌株的流行,淋球菌感染已经成为引起全球热议的公共卫生问题之一。在未有疫苗可供选择的情况下,考虑可用于临床治疗的新品种的抗生素更是刻不容缓,其中庆大霉素是一种可取的替代药物。目前,世界卫生组织和美国疾病控制和预防中心等已将庆大霉素加入淋病治疗指南和(或)常规药物敏感性监测中。本综述将对庆大霉素的临床应用、药敏监测和耐药机制等方面进行介绍。
Antimicrobials play an essential role in prevention and treatment of gonorrhoeae.However,with the emergence of isolates resistant to different antimicrobials,the infection of gonorrhoeae has become one of the most significant public health problems.In the absence of vaccines to be used,it is urgent to consider new types of antibiotics for clinical use,of which gentamicin is one of the desirable alternative drugs.Nowadays,gentamicin has been listed in WHO and US CDC guidelines for treatment and/or routine antimicrobial surveillance.This review aims to introduce the clinical use,antimicrobial surveillance and potential drug-resistance mechanism of gentamicin.
作者
朱邦勇
刘经纬
尹跃平
ZHU Bangyong;LIU Jingwei;YIN Yueping(Guangxi Institute of Dermatology,Nanning 540007,Guangxi,China;Institute of Dermatology,Chinese Academy of Medical Sciences&Peking Union Medical College,National Center for STD Control,China CDC,Nanjing 210024,Jiangsu)
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2019年第4期432-434,共3页
Chinese Journal of Aids & STD
基金
中国医学科学院医学与健康科技创新工程(2016-I2M-3-021)~~
关键词
淋球菌
庆大霉素
耐药监测
Neisseria gonorrhoeae
Gentamicin
Antimicrobial Surveillance
