摘要
目的分析不明原因不育患者血清中抗精子抗体的发生率。方法筛选不明原因不育夫妇病例 ,用ELISA检测不育患者血清中的抗精子抗体。结果患者血清共 15 3份 ,8份阳性 ,占 5 .2 3%,其中男性血清阳性率为 3.6 4%(2 / 5 5 ) ,女性血清阳性率为 6 .12 %(6 / 98) ,没有发现夫妻双方同时阳性的病例。结论不明原因不育患者的血清抗精子抗体发生率较低 ,而男性患者的阳性率比女性患者的阳性率更低。
ObjectivesTo analyze the incidence of antisperm antibody in the sera of patients with infertility of unknown causes.MethodsInfertile couples with unknown causes were screened and their serum levels of antisperm antibody were detected by ELISA.ResultsEight out of 153 serum samples from these infertile couples showed positive reaction of antisperm antibody, with an incidence of 5.23% . The serum positive rates in male patients were 3.64% (2/55); whereas those in female patients was 6.12% (6/98). Infertile couples displaying coexisted positive reaction in both sides were not found.ConclusionLow incidence of antisperm antibody is detected in the sera of infertile patients with unknown causes, the positive rate in serum samples of male patient is further lower than that of female patients.
出处
《医学临床研究》
CAS
2003年第10期766-768,共3页
Journal of Clinical Research
基金
国家自然科学基金 (No .30 2 71370 )
广东省自然科学基金 (No .0 10 398)