摘要
目的 本文探讨多普勒超声在评价阴茎海绵体内前列腺素E1(PGE1)和罂粟硷 (PAP)小剂量联合用药对勃起功能障碍 (ED)的剂量选择。方法 对 2 0例勃起功能正常组和 45例非血管性勃起功能障碍组采用不同剂量注射 ,用多普勒超声检测阴茎海绵体动脉收缩期最大流速 (PSV)和舒张期流速 (EDV)。结果 ①小剂量 (PGE110 μg +PAP 7.5mg)联合用药就可明显增加阴茎血流 ,产生良好的勃起 ,与ICI前相比有显著差异 (P <0 .0 1) ;②增加剂量注射与小剂量注射相比阴茎血流稍有增加 ,但各组之间无显著差异 (P >0 .0 5 ) ;③小剂量联合用药未出现阴茎持续勃起和局部疼痛。结论 多普勒超声可客观地评价阴茎的血流参数 ,为ICI的药物剂量选择提供依据 ,而小剂量联合用药对勃起功能障碍者能产生良好的阴茎血流 ,是治疗和筛选勃起功能障碍的一种有效方法。
Objective To study small dose of PGE1 and papaverine (PAP) for the screening erectile dysfunction by intra cavernous injection (ICI). Methods Twenty males with normal erectile function and 45 cases with non vasculogenic erectile dysfunction were observed by Doppler sonography and the peak systolic velocity (PSV) and the end diastolic velocity (EDV) were measured. Results ①Small dose (PGE1 10μg+PAP 7.5mg) injection could effectively increase the penile blood and bring good erection. ②Additive dose increase little flowing blood, it is non significant compared with small dose ( P > 0.05 ). ③Combined using of small dose did not bring local ache and priapism. Conclusion The combined use of small dose vasodilators can bring out good hemodynamics in penis for erectile dysfunction. [
出处
《中国医学影像技术》
CSCD
2003年第9期1202-1203,共2页
Chinese Journal of Medical Imaging Technology
关键词
多普勒超声
勃起功能障碍
联合小剂量
Doppler sonography
Erectile dysfunction
Small dose injection
