摘要
目的 分析支气管哮喘伴胃食管反流患者与支气管哮喘无胃食管反流患者的胃镜下食管粘膜病理差异 ,哮喘的轻重 ,肺功能及喘、咳周平均日次数。方法 将 5 4例就诊的支气管哮喘病人随机分为两组 ;支气管哮喘无胃食管反流症状组 ( 1组 ) 3 0例 ,支气管哮喘伴胃食管反流症状组 ( 2组 ) 2 4例 ,所有病人均经食管胃镜检查同时测定FEV1 、PEF和喘、咳周平均日次数 ,两组进行比较和统计学分析。结果 2组均有食管粘膜的病理变化 ,1组部分病人也存在着潜在食管粘膜的病理变化 ,两组差异非常显著 ;两组病情严重程度差异有显著性 ,2组的病情明显重于 1组 ;两组FEV1 、PEF值差异有显著性 ,2组的FEV1 、PEF值明显小于 1组 ;2组的喘、咳周平均日次数明显大于 1组 ,差异有显著性。结论 胃食管反流对支气管哮喘患者的肺功能有一定的影响 ;伴胃食管反流支气管哮喘病情较重 ;
Objective To investigate the correlation between gastroesophageal reflux (GER) and bronchial asthma.Methods 54 patients with bronchial asthma were divided into two groups,group 1 (n=24 ) with GER and group 2 (n=30) without GER.All the patients were examined by gastrointestinal fiberscope,at the same time FEV 1,PEF and the score of the symptoms were determined.The indexes of both groups were compared and analyzed statistically.Results The pathlogical changes on esophagus membrance in group 1 were much more obvious than those of group 2 and the patient's condition in group 1 was much severer than that in group 2.There were significant differences in the score of the FEV 1,PEF and the score of the symptoms between two groups.Conclusion GER has some effects on lung function of patients with bronchial asthma,and the symptoms are more severer in patients with GER.There may be potential GER in patients without the symptoms of GER.
出处
《河北医药》
CAS
2003年第10期730-731,共2页
Hebei Medical Journal
