摘要
目的观察幽门螺杆菌 (Hp)与胃及十二指肠粘膜病理组织学表现之间的关系。方法对 6 0例慢性胃炎和 2 2例十二指肠溃疡患者经胃镜分别从胃窦、胃体、十二肠球部取活检 ,进行组织学检测。结果在活动性胃炎中无论是胃窦部或胃体部 Hp检出率近 10 0 % ,显著高于活动性十二指肠球炎的球部 Hp的检出率。胃窦部 Hp总检出率及活动性炎症的发生率均显著高于胃体部及十二指肠球部。2 2例十二指肠球部溃疡 Hp在球部的检出率为 5 4% ,显著低于其在胃窦部组织中 Hp10 0 %的检出率。结论 Hp感染是胃粘膜活动性炎症的重要原因 ,并以此为基础发展为重度粘膜炎及溃疡病 ,因此 ,对某些慢性胃炎患者应及早进行
Objective To evaluate the relationship between Helicobacter pylori (Hp) infection and pathohistological presentation of gastric and deuodenal mucosa.Methods The gastritis biopsies were taken through endoscopy from each gastric body,antrum and duodenum in 60 patients with gastritis and 22 patients with duodenal ulcer respectively for the examination of histology.Result The positive rate of Hp was nearly 100% in active chronic gastritis which was significantly higher than that of active duodenitis.The total detecting rate of Hp infection and incidence rate of active inflammation in antrum were obviously higher than that of gastric body and duodenal bulb.The detecting rate of Hp infection of duodenal bulb in 22 cases of duodenum ulcer was 54% which was significantly lower than that of antrum.Conclusion The Hp infection is a very important pathogenic factor of active inflammation in gastric mucosa on the basis of which the severe inflammation of mucosa and ulcer development.Therefore the early elimination of Hp is very important.
出处
《中国综合临床》
北大核心
2001年第5期356-357,共2页
Clinical Medicine of China
