摘要
①目的 比较电化学发光法测定血清肌酸激酶同工酶 (CK MB)含量与酶法测定CK MB活性在急性心肌梗死 (AMI)诊断中的可靠性。②方法 应用电化学发光法与酶法分别测定了 2 5例急诊AMI病人、2 0例非AMI病人和 30例健康人的CK MB含量和活性。③结果 AMI病人的CK MB含量和活性到达峰值的时间相同 ,CK MB含量和活性AMI病人均高于非AMI病人和健康人 ,差异有显著性 (F =9.81,q =10 .5 8～ 15 .0 9,P <0 .0 1) ;非AMI病人CK MB活性亦高于健康人 ,差异有显著性 (F =5 .0 7,q =12 .71,P <0 .0 5 )。 ④结论 电化学发光法测定CK
Objective To evaluate the reliability of serum creatine kinase isoenzyme(CK-MB) content determined by electrochemiluminescence (ECL) and its activity by enzymology assay in the diagnosis of acute myocardial infarction( AMI). Methods Serum CK-MB content and its activity were determined by ECL and enzymology respectively in 25 AMI patients, 20 non-AMI patients, and 30 healthy persons. Results CK-MB activity and content in serum of AMI patients reached peak at the same time, and were significantly higher than that of non-AMI patients and healthy persons, the difference was significant (F=9.81, q=10.58-15.09, P<0.01).The CK-MB activity in non-AMI patients was also significantly higher than that in healthy persons ( F=5.07,q=12.71,P<0.05). Conclusion Detection of serum CK-MB content by ECL is reliable in the diagnosis of AMI.
出处
《齐鲁医学杂志》
2003年第4期383-384,共2页
Medical Journal of Qilu
