摘要
目的研究骨肿瘤患者临床特征与癌因性疲乏的相关性。方法回顾性分析998例骨肿瘤患者的临床资料及相关数据,通过横断面研究,以社会支持量表、疲乏Piper量表、记忆症状简易评价表完成调查分析。结果 386例骨肿瘤患者出现癌因性疲乏,其发生率达到38.68%。患者疲乏总分是(3.92±2.07)分:患者行为维度是(4.85±3.12)分、认知/情绪维度是(1.91±1.27)分、情感维度是(4.53±2.48)分、感觉维度是(4.22±2.86)分。骨肿瘤患者社会支持状况评分中,社会支持总分为(37.69±6.11)分,客观支持评分为(10.28±2.62)分,主观支持评分为(19.85±3.41)分,对支持的利用度评分为(7.53±2.11)分。癌因性疲乏患者(n=386)与无癌因性疲乏患者(n=612)单因素社会支持分析显示,社会支持总分、主观支持评分、对支持的利用度评分对比,呈显著差异(P<0.05),客观支持评分对比,不具差异(P>0.05)。Logistic单因素、多因素回归分析显示,出现疼痛、昏睡、咳嗽、体重下降、食欲减退、头晕、排尿不适、气紧、呼吸困难、便秘、感觉悲伤、感觉紧张、焦虑者的癌因性疲乏发生率高于未出现上述症状者(P<0.05)。结论骨肿瘤患者癌因性疲乏的发生,与社会支持、临床症状均有密切关系,针对患者实施个体化治疗,避免不良反应,改善生活质量,同时增加社会支持,帮助患者调整心理状态,从而提高临床疗效。
Objective To study the relationship between clinical features and cancer related fatigue in patients with bone tumor. Methods Clinical data of 998 cases of bone tumors were retrospective analyzed through the cross-sectional study,social support scale,Piper scale,memory fatigue symptoms simple evaluation table. Results 386 cases of patients with bone tumors had cancer related fatigue,the incidence was 38. 68%,the total scores of fatigue was( 3. 92 + 2. 07),behavior dimension was( 4. 85 +3. 12),cognitive / emotional dimension was( 1. 91 + 1. 27) points,the emotional dimension was( 4. 53 + 2. 48),sense of dimension was( 4. 22 + 2. 86) points. Social support status of patients with bone tumor,total score of social support was( 37. 69 + 6. 11),objective support score was( 10. 28 + 2. 62),subjective support score was( 19. 85 + 3. 41),the utilization of support score was( 7. 53 + 2. 11) points. Single factor analysis showed hat social support,the total score of social support,subjective support score,the score comparison with support between patients with cancer related fatigue( n = 386) and non cancer related fatigue( n = 612)had significant difference( P < 0. 05),objective support score comparison had no difference( P > 0. 05). Single factor,multi-factor logistic regression analysis showed that pain,drowsiness,cough,weight loss,loss of appetite,dizziness,dysuria,gas tight,difficulty in breathing,constipation,sadness,tension,anxiety cancer related fatigue rate in patients with cancer related fatigue was higher than non cancer related fatigue persons( P < 0. 05). Conclusion Occurrence of cancer-related fatigue in bone tumor is related to social support and clinical symptoms. Individualized treatment can avoid adverse reactions,improve the quality of life,increase social support,help adjust the psychological state of patients,so as to improve the clinical efficacy.
出处
《实用癌症杂志》
2015年第3期463-465,共3页
The Practical Journal of Cancer
关键词
社会因素
临床症状
不良反应
癌因性疲乏
骨肿瘤
Social factors
Clinical symptom
Adverse reaction
Cancer related fatigue
Bone tumor
