摘要
目的探讨经皮椎体成形术(PVP)治疗老年胸腰椎转移性肿瘤压缩骨折的临床疗效及安全性。方法选择86例行PVP治疗的老年胸腰椎转移性肿瘤压缩骨折的患者为研究对象,比较手术前后伤椎前缘高度、Cobb角、视觉模拟评估法(VAS)评分、生活质量,并对并发症发生情况进行分析。结果患者术后1 d、3个月及6个月伤椎前缘高度及Cobb角均显著优于术前(P<0.05)。与术前相比,术后1 d VAS评分开始显著下降(P<0.05);术后3个月完全缓解、部分缓解及治疗无效患者的VAS评分依次升高(P<0.05)。术后6个月患者简明健康状况调查表(SF-36简表)显示躯体功能、机体疼痛、活力及总健康状况维度评分显著优于术前(P<0.05)。术中8例患者发生骨水泥渗漏,未出现脊髓受压、肺栓塞及骨水泥毒副作用。结论 PVP治疗老年胸腰椎转移性肿瘤压缩骨折疗效确切,止痛效果及安全性好,患者生活质量得到提高。
Objective To explore the effects and safety of percutaneous vertebral plastic operation ( PVP) for elderly metastatic tumors thoracolumbar vertebral fractures .Methods 86 cases with metastatic tumors thoracolumbar vertebral fractures underwent PVP treatment were selected as research subjects .Anterior vertebral height,Cobb angle,VAS scores,life quality before and after operation and adverse rates were analyzed .Results Anterior vertebral height and Cobb angle on 1 day,3 and 6 months after operation were superior to pre-operation (P<0.05);Comparison with pre-operation,VAS scores greatly decreased on 1 day after operation (P<0.05);VAS scores on 3 months gradually increased in the patients of complete remission ,partial remission and ineffective treatment (P<0.05);Physical functioning,bodily pain,vitality and the general health state scores of SF-36 scale on 6 months after surgery were superior to pre-operation (P<0.05).Bone cement leakage occurred in 8 patients;No spinal com-pression,pulmonary embolism and bone cement adverse reaction were found in the patients .Conclusion PVP for elderly meta-static tumors thoracolumbar vertebral fractures have ideal clinical effect with good relief effect and safety .The life qualities are im-proved.
出处
《实用癌症杂志》
2014年第9期1174-1176,共3页
The Practical Journal of Cancer
关键词
椎体转移瘤
骨折
经皮椎体成形术
Vertebral metastasis
Fracture
Percutaneous vertebral plastic operation
