摘要
研究食品添加剂脱氢醋酸钠对动物抗氧化能力的影响。以仔猪作为实验动物模型,选用10日龄哺乳仔猪(杜×长×大)192头,随机分成4组(每组4个重复,每重复12头),饲喂不含脱氢醋酸钠的基础日粮(对照组)、基础日粮中分别添加脱氢醋酸钠0.02%(实验组Ⅰ)、0.1%(实验组Ⅱ)和0.2%(实验组Ⅲ)的日粮,实验期42 d。结果表明:与对照组相比,1)仔猪51 d体质量,Ⅲ组显著降低13.26%(P<0.05),Ⅰ、Ⅱ组无显著差异(P>0.05);2)Ⅲ组仔猪血清超氧化物歧化酶(superoxide dismutase,SOD)活力极显著降低(P<0.01),总抗氧化能力(total antioxidant capacity,T-AOC)显著降低(P<0.05),而Ⅰ、Ⅱ组仔猪血清抗氧化指标均无显著差异(P>0.05);3)仔猪肝脏丙二醛(malondialdehyde,MDA)含量,除Ⅲ组外,Ⅰ(P<0.01)、Ⅱ(P<0.05)组均有明显升高。因此,日粮中添加0.2%脱氢醋酸钠,明显降低仔猪的抗氧化能力,食品中使用高剂量脱氢醋酸钠存在一定的健康风险。
The effects of sodium dehydroacetate on antioxidant capacity in weaned piglets were investigated. A total of 192 crossbreds(Duroc × Landrace × Yorkshire) piglets at 10 days of age were randomly divided into 4 groups with 4 replicates consisting of 12 animals each. They were weaned and fed with basal diet(control group), basal diet supplemented with 0.02%(group Ⅰ), 0.1%(group Ⅱ) and 0.2%(group Ⅲ) sodium dehydroacetate, respectively. The experiment lasted for 42 days. The results showed that when comparing with the control group: 1) the weight of the 51-day-old piglets in group Ⅲwas significantly decreased by 13.26%(P < 0.05), while groups Ⅰ and Ⅱ had no significant difference(P > 0.05); 2) the serum total superoxide dismutate(T-SOD) in group Ⅲ was decreased highly significantly(P < 0.01), in addition to a significant reduction in serum total antioxidant capacity(T-AOC)(P > 0.05). But the serum antioxidant indices in groups Ⅰand Ⅱ had no significant difference; and 3) the liver malondialdehyde(MDA) contents in groups I(P < 0.01) and Ⅱ(P < 0.05) but not in group Ⅲ were increased significantly. These results indicate that the diet containing 0.2% sodium dehydroacetate could significantly decrease the TAC in piglets. Thus some potential health risks may be caused by using high levels of sodium dehydroacetate in food.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2014年第11期54-57,共4页
Food Science
基金
江苏高校优势学科建设工程资助项目
关键词
脱氢醋酸钠
断奶仔猪
抗氧化能力
sodium dehydroacetate
weaned piglets
antioxidant capacity
