摘要
目的比较腹腔镜与开放手术治疗早期局限性前列腺癌的临床疗效及安全性。方法选择77例早期局限性前列腺癌患者,分为观察组40例和对照组37例,观察组采用腹腔镜前列腺癌根治术,对照组采用经耻骨后前列腺癌根治术,比较二者治疗效果。结果观察组患者手术时间与对照组相似,差异无统计学意义(P>0.05);而术中出血量少于对照组,差异有统计学意义(P<0.05)。观察组患者引流管拔除时间和留置导尿时间与对照组相似,差异无统计学意义(P>0.05);而观察组患者胃肠功能恢复时间、术后下床活动时间和术后住院时间均优于对照组,差异有统计学意义(P<0.05)。观察组术后并发症发生率30%,低于对照组的50%,差异有统计学意义(P<0.05)。两组患者术后1年及术后2年生化复发率相似,差异无统计学意义(P>0.05)。结论腹腔镜手术治疗局限性前列腺癌具有创伤小、恢复快、并发症少,而且在肿瘤控制方面与开放性手术具有相似的效果。
Objective In order to compare clinical effects and safety of laparoscope and open operation for treatment of early local prostate cancer. Methods 77 cases of patients with early local prostate cancer were selected in this study,they were distributed into the observation group 40 cases and control group 37 cases. The patients in the observation group were treated with laparoscopic radical prostatectomy,and the patients in the control group were treated with radical retropubic prostatectomy,thera-peutic effects of the two groups were compared. Results Operation time of the two groups was similar,the difference had no statis-tical significance( P>0. 05 ) , intraoperatve blood soss of the patients in the observation group was less than that in the control group,the difference had statistical significance(P<0. 05). Drainage tube removal time and indwelling catheter time of the patients in the observation group were similar to that in the control group,the differences had no statistical significance(P>0. 05). Gastro-intestinal function recovery time,postoperative activity time and postoperative hospitalization duration of the patients in the observa-tion group were superior to that in the control group. The differences had statistical significance ( P<0. 05 ) . Occurrence rate of postoperative complications in the observation group was 30%,while occurrence rate of postoperative complications in the control group was 50%,The difference had statistical significance(P<0. 05). In the observation group,biochemical recurrence rate of the patients within 1 year or two years after operation was similar to that in the control group,the difference had no statistical signifi-cance(P>0. 05). Conclusion Advantages of laparoscopic surgery for treatment of prostate cancer include low trauma,fast recov-ery,few complications,in addition,curative effects of laparoscopic surgery for tumor control were similar to that of open opera-tions.
出处
《四川医学》
CAS
2014年第11期1443-1446,共4页
Sichuan Medical Journal
