摘要
目的比较腹腔镜下卵巢巧克力囊肿剥除术中注水分离法与钝性分离法对术后卵巢储备功能的影响。方法选取2017年4月至2018年4月于温州康宁医院接受卵巢巧克力囊肿治疗的115例患者作为研究对象,按照患者手术中巧克力囊肿剥除方法的不同,将使用注水分离法的患者设为观察组(58例),使用钝性分离法的患者设为对照组(57例)。比较两组患者的血清卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E_2)、抗苗勒管激素(AMH)的水平,手术情况和妊娠情况。结果观察组术后术3个月、术后5个月血清FSH水平均显著低于对照组(t值分别为2.134、2.158,均P<0.05),而术后5个月E_2水平显著高于对照组(t=2.263,P<0.05)。观察组术后3个月、术后5个月血清AMH水平均显著高于对照组(t值分别为2.135、2.143,均P<0.05)。观察组患者剥除病灶厚度、卵巢皮质剥除厚度、手术时间、手术出血量均显著低于对照组(t值分别为2.314、2.275、11.452、13.764,均P<0.05)。观察组的妊娠率显著高于对照组,疾病复发率显著低于对照组(χ~2值分别为9.162、5.842,均P<0.05)。结论与钝性分离法相比较,行注水分离法卵巢巧克力囊肿剥除术后,患者的卵巢功能恢复较早,且能够减轻卵巢组织损伤、提高患者手术后的妊娠率。
Objective To compare the effect of water injection separation and blunt separation on ovarian reserve function after laparoscopic ovarian chocolate cystectomy. Methods A total of 115 patients who underwent ovarian chocolate cystectomy in Kangning Hospital of Wenzhou City from April 2017 to April 2018 were enrolled. The patients were divided into observation group(58 cases) with water injection separation and control group(57 cases) with blunt separation. The levels of serum follicle stimulating hormone(FSH), luteinizing hormone(LH), anti Miillerian hormone(AMH), estradiol(E2), surgery situation and pregnancy were compared between two groups. Results The serum FSH levels at 3 months and 5 months after operation in the observation group were significantly lower than in the control group(t value was 2.134 and 2.158, respectively, both P<0.05), but the serum E2 level was significantly higher than the control group(t=2.263,P<0.05). The AMH levels at 3 months and 5 months after operation in the observation group were significantly higher than in the control group(t value was 2.135 and 2.143, respectively, both P<0.05). The thickness of the lesion removed, the thickness of the ovarian cortex removed, the operation time and the amount of blood loss in the observation group were significantly lower than in the control group(t value was 2.314, 2.275, 11.452 and 13.764, respectively, all P<0.05). The pregnancy rate in the observation group was significantly higher than in the control group and the disease recurrence rate was significantly lower compared with that in the control group(χ2 value was 9.162 and 5.842, respectively, both P<0.05).Conclusion Compared with the blunt separation method, the ovarian function recovery of the patients with ovarian chocolate cysts after water injection separation method is earlier, and can reduce the ovarian tissue damage and improve the pregnancy rate after surgery.
作者
马远东
刘小彩
毛凌哲
MA YuANDong;LIU Xiaocai;MAO Lingzhe(Kangning Hospital of Wenzhou City,Zhejiang Wenzhou 325000,China)
出处
《中国妇幼健康研究》
2019年第2期240-243,共4页
Chinese Journal of Woman and Child Health Research
关键词
注水分离法
钝性分离法
卵巢巧克力囊肿
卵巢储备功能
water injection separation
blunt separation
ovarian chocolate cyst
ovarian reserve function
