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应用莫西沙星治疗急性鼻窦炎的效果分析

To observe the clinical efficacy and adverse reactions of moxifloxacin in patients with acute sinusitis treatment application
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摘要 目的 :探讨分析应用莫西沙星治疗急性鼻窦炎的临床效果。方法 :选取2012年9月~2014年1月间我院收治的急性鼻窦炎患者90例作为研究对象,采用随机数字表法将其分为对照组(45例)和观察组(45例),应用阿莫西林为对照组患者进行治疗,应用莫西沙星为观察组患者进行治疗,观察对比两组患者的临床疗效及不良反应的发生情况,并将对比的结果及两组患者的临床资料进行回顾性的分析。结果 :对照组患者治疗的总有效率为64.44%,观察组患者治疗的总有效率为91.11%,观察组患者的临床疗效明显优于对照组患者,差异显著(P<0.05),具有统计学意义。观察组患者的不良反应发生率为13.33%,对照组患者的不良反应发生率为40.00%,观察组患者的不良反应发生率明显低于对照组患者,差异显著(P<0.05),具有统计学意义。结论 :应用莫西沙星治疗急性鼻窦炎的临床效果显著,值得在临床上推广应用。 Objective: To explore the clinical efficacy and adverse reactions of moxifloxacin in patients with acute sinusitis treatment application. Methods: selected in our hospital from 2012 September to 2014 January, diagnosed with acute sinusitis and in 90 patients as the research object, randomly divided into using amoxicillin treatment of control group 45 cases and with moxifloxacin treatment observation group of 45 cases, the clinical efficacy of the two groups and the adverse reactions of comparison. Results: after treatment the total effective rate (90%) was significantly better than the control group (65%), gastrointestinal reactions occurred in the observation group after treatment, nausea, bloating, dizziness, etc. A total of six cases of adverse reactions, the rate were 13.33%, the control group of gastrointestinal reactions after treatment, nausea, bloating, dizziness and other adverse reactions there were 18 cases, the rate was 40.00%, between the two groups was statistically significant (P <0.05). Conclusion: moxifloxacin treatment of patients with acute sinusitis can achieve better clinical efficacy, worthy of promotion in clinical applications.
作者 陈勇
出处 《当代医药论丛》 2014年第20期140-142,共3页
关键词 急性鼻窦炎 莫西沙星 临床疗效 不良反应 acute sinusitis moxifloxacin clinical efficacy adverse reactions
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