摘要
目的 研究温清饮对复发性口疮患者疗效及免疫功能的影响。方法 用放射免疫分析(RIA)和酶联免疫吸附试验(ELISA)检测温清饮治疗前后复发性口疮患者血清白介素2 (IL-2)、可溶性白介素2受体(sIL-2R)及肿瘤坏死因子α(TNF-α)水平的变化。结果 温清饮治疗后显效者31例(64.6％),有效者13例(27.1％),无效者4例(8.3％)。治疗后复发性口疮患者血清IL-2水平升高(P<0.01),接近于对照组(P>0.05);sIL-2R、TNF-α水平下降(P<0.05,P<0.01),但仍高于对照组(P<0.05)。结论 温清饮可以调节复发性口疮患者失常的细胞免疫功能,治疗复发性口疮。
Objective To investigate the effect of Wenqing Decoction on clinical efficacy and immunologic function of the patients with recurrent aphthous ulcer( RAU) . Methods The changes of serum interleukin - 2( IL - 2) , soluble interleukin - 2 receptor( sIL - 2R) and tumor necrosis factor α(TNFα) levels in RAU patients before and after treatment with Wenqing Decoction were detected by RIA and ELISA. Re-SultsThe obvious efficacy happened in 31 cases (64.6 % ), efficacy in 13 cases (27.1 % ) and no efficacy in 4 cases (8.3%) after treatment. Serum IL - 2 level in the patients with RAU after treatment significantly increased ( P < 0.01), close to those of the controls ( P > 0.05); serum sIL - 2R and TNFa levels in the patients with RAU markedly reduced( P < 0.05, P < 0.01), but were still higher than those of the controls ( P < 0.05 ). Conclusion Wenqing Decoction might regulate abnormal cellular immunologic function of the patients with RAU.
出处
《口腔医学》
CAS
2003年第4期230-231,共2页
Stomatology
关键词
复发性口疮
温清饮
免疫功能
疗效
Recurrent aphthous ulcer
Wenqing Decoction
Immunologic function
Efficacy
