摘要
应用免疫组织化学方法研究了成年Wistar大鼠下丘脑的冠状、矢状和水平3种切面上第三脑室室管膜下神经丛(SEP)中的催产素(OXT)免疫阳性神经元及其树突所构成的丛(OXT-SEP)的形态及分布。OXT-SEP内细胞均为大细胞神经分泌神经元,位于室管膜细胞之间或其下。树突多平行于室管膜走行,终止于室管膜细胞之间或膜下,个别树突可伸入脑室中,部分树突内有空泡状结构,且有成束走行趋势。整个OXT-SEP分为背、腹两部分,前者密集而广泛,大致对应室旁核3个大细胞亚核,前、后大细胞亚核亦发出树突,伸入背部丛;背部丛树突依其部位有规律伸展,主要向前、后等方向。腹部丛是位于第三脑室腹部及底部的松散细胞群,树突主要向上、下及前下、后上等方向伸展。不同部位的细胞及树突间可相互交错、邻接。以上结果表明,OXT-SEP的细胞成分不仅与第三脑室接触广泛,而且与之极接近,从而建立了与脑脊液进行信息交换的结构基础。
Immunohistochemical method was used to investigate the morphology and distribution of the oxytocin immunoreactive (OXT-ir) neurons and their dendrites in the subependymal plexus (SEP) around the third ventricle (OXT-SEP). The OXT-ir neurons were of magnocellular neurosecretory type which often intercalated between the ependymal cells, their dendrites were generally long and straight and mostly paralleled to or traveled within the ependyma,some of them could protrude into the ventricle, and most of them appeared heavily vacuous and have a strong tendency of grouping into fascicles. The plexus was composed of dorsal and ventral parts, the former corresponding to the extent of the magnocellular paraventricular nuclei and was extensive and dense, the dendrites were well organized; the latter was more sparse. The cell bodies and dendrites within and between different parts might mix or contact with each other. The functional significance of the plexus is discussed.
出处
《解剖学报》
CAS
CSCD
北大核心
1992年第2期139-144,共6页
Acta Anatomica Sinica
关键词
第三脑室
室管膜下丛
催产素
大鼠
Third ventricle
Subependymal plexus
Oxytocin
Immunohistochemistry
Rat
