摘要
目的介绍自由体积理论及其应用。方法通过检索国内外文献,概述自由体积的基本原理,并对这一理论在描述药物扩散和其他传质现象中的应用进行综述。结果和结论用自由体积理论,可以成功预测共聚物、水凝胶以及生物膜等体系中的扩散现象。
Objective To introduce free volume theory and its application. Methods According to the references in recent years, the basic principle of free volume theory is summarized, and the application of this theory in the description of drug diffusion and other mass transfer phenomenon is reviewed. Results and Conclusions This theory has been used to successfully predict the diffusivity of solutes in copolymer,hydrogel or biological membrane systems.
出处
《中国药剂学杂志（网络版）》
2004年第1期7-13,共7页
Chinese Journal of Pharmaceutics：Online Edition
关键词
药剂学
药物扩散
综述
自由体积理论
pharmaceutics
drug diffusion
review
free-volume theory
