摘要
目的 :了解我院真菌尿路感染现状 ,探讨防治对策。方法 :回顾分析 1998～ 2 0 0 0年我院医院感染调查中 73例真菌尿路感染的临床特点。结果 :平均年龄 5 4 4 9岁 ,≥ 6 0岁占 4 2 4 7% ,平均住院日5 4 76d ;见于多种基础疾病 ,与恶性肿瘤、长期卧床、危重疾病有关 ;发生真菌感染前抗生素使用率 10 0 % ,78 0 8%联用两种以上抗生素 ,平均使用抗生素时间为 (35± 14 )d ;感染前应用激素者 2 7,4 0 % ,化疗16 4 4 % ,导尿等泌尿操作 4 7 95 % ;临床表现不典型 ,抗真菌治疗效果欠佳 ,病死率 2 4 6 6 %。结论 :年龄大、住院时长、长期卧床及需长期应用抗生素者 ,无论是否导尿 ,均易发生真菌尿路感染 ,应随时监测 ,以便及时采取综合治疗措施 ,降低病死率。
Objective:To understand the clinical features of nosocomially acquired fungal urinary tract infections(NAFUTI).Methods:Seventy-three cases who developed nosocomial fungal urinary tract infections during the year 1998 to 2000 were analyzed. Results: 42.47%of the cases were over 60 and the average age was 54.76;The average in-hospital days was 54.7.6;Most of the NAFUTI patients had multiple serious underlying deseases,all the patients had received antimicrobial agents as long as about 35 days,among them 78.08%had received more than two kinds of antimicrobial agents;Only 47.95%of the NAFUTI patients were associated with urethral instrumentations;Most patients had no clinical symptoms referable to the urinary tract;The mortality rate was 24.66%. Conclusion:Aging,Long-term hospitalization,long-term antibacterial therapy,critical underlying diseases were associated with NAFUTI.
出处
《中国微生态学杂志》
CAS
CSCD
2003年第3期165-165,167,共2页
Chinese Journal of Microecology
