摘要
反刍动物肝片吸虫病在世界范围内对畜牧业造成严重的经济损失,需要研制疫苗进行防制。本文介绍动物肝片吸虫病的保护性免疫应答的表现形式,对保护性免疫应答效应机制和寄生虫免疫逃避机制展开讨论,阐述选择疫苗候选抗原的不同策略,最后探讨研制抗肝片吸虫疫苗所受到的限制因素。
Fasciolosis is an economically important disease in ruminants which needs prophylaxis by vaccination. The manifestations of protective immune response antiFasciola hepatica of hosts, the immune response effector mechanisms, and the immune escape mechanisms of parasite were reviewed in this paper. The different strategies of selection of vaccine candidates and the limits of development of a vaccine antiF. hepatica were also discussed.
出处
《广西农业生物科学》
CAS
CSCD
2003年第2期147-152,共6页
Journal of Guangxi Agricultural and Biological Science
基金
中法合作项目(PRAB99-04)
广西自然科学基金资助项目(桂科自0007005)
