摘要
甘露醇是一种重要的海洋生物活性物质,既可用作原料药配制甘露醇注射液;也可作为药用辅料与许多制剂配伍使用;同时还可以合成一系列衍生药物。现系统阐述甘露醇作为原料药和药用辅料的具体应用,并重点论述目前其药用衍生物的制备方法、性质和医药用途。
Mannitol is a kind of major marine bio-products with important biological activities. It is not only used in injection as raw material, but also used with other medicine as supplemental composition. Simultaneously, it is used for synthesis of a series of derivative medicines. The specific application of mannitol as raw materials and excipient was reviewed in detail. And the synthetic methods, properties and medical application of every derivative medicine were introduced.
出处
《中国海洋药物》
CAS
CSCD
2003年第3期57-61,共5页
Chinese Journal of Marine Drugs
基金
国家杰出青年科学基金(项目编号:49925614)
中国科学院方向性创新项目(项目编号:KZCX3-SW-215)
关键词
甘露醇
海洋生物
活性物质
制备方法
研究进展
Mannitol and its derivatives
medicinal application
Biological activities