摘要
目的 研究绞股蓝总皂甙 (gypenoside ,GP)对肾性贫血大鼠血浆促红细胞生成素 (erythropoietin ,EPO)含量的影响。方法 用腺嘌呤灌胃建立大鼠肾性贫血模型 ,治疗组加用GP。用胎鼠肝细胞法测定EPO。结果 治疗组肾功能明显改善 ,EPO含量明显升高。结论 GP具有改善肾功能 ,升高血浆EPO水平的作用 。
Objective To investigate the effect of gypenoside (GP) on erythropoietin in rats with chronic renal anemia. Methods We established a rat model of chronic renal anemia with adenine, which was then treated with gypenoside. Results Gypenoside significantly improved the rats' renal function and increased the erythropoietin level in plasma. Conclusion Gypenoside can improve rat renal function and increase erythropoietin level in plasma, and can be used to treat chronic renal anemia.
出处
《西安交通大学学报（医学版）》
CAS
CSCD
北大核心
2003年第3期273-274,289,共3页
Journal of Xi’an Jiaotong University（Medical Sciences）
基金
陕西省卫生厅资助项目 (No .40 )
