摘要
目的:对近5年临床肺炎克雷伯菌感染分布情况和耐药性进行分析。方法:2007年1月～2011年12月从临床标本中分离出的肺炎克雷伯氏菌相关资料进行回顾性分析。结果:645株肺炎克雷伯菌主要来自痰液,占69.5%,其次为尿液及血培养,分别占14.0%、8.4%;主要分布于高压氧科、呼吸内科、ICU,分别占14.3%、10.2%、9.1%;产ESBLs肺炎克雷伯菌检出179株,检出率为27.8%。结论:肺炎克雷伯菌由于产ESBLs菌株易检出率高,对常用抗菌药物多呈耐药性,对肺炎克雷伯菌进行及时准确鉴定和药敏分析,把握耐药趋势,对指导临床合理用药有重大意义。
Objective To investigate the clinical distribution and drug resistance of Klebsiella pneumoniae in nearly five years.Methods Data of Klebsiella pneumoniae isolated from clinical specimens from January 2007 to December 2011 were retrospectively analyzed.Results Majority of the 645 strains of Klebsiella pneumoniae were isolated from sputum,accounting for 69.5%,followed by urine and blood culture,accounting for 14.0% and 8.4% respectively.The strains were mainly distributed in Department of Hyperbaric Oxygen and respiratory medicine department and ICU,accounting for 14.3% and 10.2%,9.1% respectively;179 strains producing ESBLs enzyme were detected,with detection rate of 27.8%.Conclusion Since there are ESBLs-producing Klebsiella pneumoniae strains with a high detection rate,it presents multi-drug resistance to common antibiotics.It is effective to direct reasonable clinical medication by making timely identification and antimicrobial susceptibility analysis,and acquiring the tendency of drug-resistance of Klebsiella pneumoniae.
出处
《中国美容医学》
CAS
2012年第12X期257-258,共2页
Chinese Journal of Aesthetic Medicine
关键词
肺炎克雷伯菌
耐药性
抗菌药物
超广谱Β内酰胺酶
Klebsiella pneumoniae,Drug Resistance
Antibiotics,Extended spectrum Beta-lactamases
