摘要
目的 探讨女阴尖锐湿疣及假性湿疣的临床病理特点及鉴别诊断。方法 对 30 4例患者的临床病理特点进行观察比较 ,其中 88例做免疫组化人乳头瘤病毒 (HPV)检测。结果 部位 :尖锐湿疣多为两个以上部位同时发生 (4 4 .5 6 % ) ,而假性湿疣多只限于一个部位 (80 .18% ) (P <0 .0 1)。局部表现 :两者均形成乳头状突起 ,但尖锐湿疣常融合成菜花状。组织学观察 :对两组的 8项病理变化进行比较分析均有显著性差异 (P <0 .0 1)。免疫组化染色 :尖锐湿疣细胞核阳性率为 6 0 .38% ,假性湿疣阴性。
Objectives To explore the clinicopathological characters and its differential diagnosis of Condyloma acuminatum and pseudo-condyloma in female vulva.Methods To observe and compare clinicopathological characters in 304 cases,including 88 cases tested for HPV by immunohistochemistry.Results Affected areas:The condyloma far often occure simultaneously at more than two sites,while the pseudo-condyloma,most of them just confined to a single area(P<0.01).Local apperance:The papillapy process is a common feature of these two lesions.However,the condyloma acuminatum often mixed the shape of a cauliflwer.Histological observations:There was significant difference to analyse 8 items pathological changes in two groups(P<0.01).Immulohistochemical staining:The positive rate of HPV detection in condyloma cells was 60.38%,which was negative in pseudo-condyloma cells.Conclusions Diagnostic koilocytes and the positive HPV results are two major evidences in the diagnosis of condyloma acuminatum,as well as in its differentiation from pseudo-condyloma.
出处
《宁夏医学杂志》
CAS
2003年第4期211-212,共2页
Ningxia Medical Journal
关键词
尖锐湿疣
病理学
鉴别诊断
假性湿疣
Condylomata acuminata
Pathology
Diagnosis,differential
