摘要
在我国,慢性肾脏病(CKD)的患者人数众多,已成为我国又一重要的公共卫生问题,成为继高血压、糖尿病、冠心病、脑卒中四大慢病以外的又一威胁人类健康的慢性疾病。20世纪晚期以来,随着社会老龄化进程的加快,CKD的发病率也逐渐升高。而CKD的预后终点事件包括:全因死亡、心血管事件(CVD)、急性肾损伤(AKI)、快速肾功能下降(RKFD)、终末期肾病(ESRD)。因此,CKD预后的评估以及危险因素分析对于CKD患者的早期发现、干预和管理、避免漏诊及过度诊断都尤为重要。本文着重介绍CKD患者不同预后事件的危险因素及胱抑素C在预后方面的风险评估。
In China,the number of patients with chronic kidney disease( CKD) has become an important public health problem,and it has become a chronic disease that threatens human health in addition to the four major chronic diseases of hypertension,diabetes,coronary heart disease and stroke. Since the late twentieth century,with the acceleration of aging,the incidence of CKD is also increasing. The end points of CKD are all-cause death,cardiovascular events( CVD),acute kidney injury( AKI),rapid renal function decline( RKFD),and end-stage renal disease( ESRD). Therefore,the assessment of the prognosis of CKD and the analysis of risk factors are particularly important for the early detection,intervention and management in CKD patients,and the avoidance of missed diagnosis and excessive diagnosis. This article focuses on the risk factors in CKD patients with different prognosis and the risk assessment of cystatin C in the prognosis.
作者
王旭
马清
WANG Xu;MA Qing(Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China Corresponding author: MA Qing,E-mail: maqing3@163. com)
出处
《临床肾脏病杂志》
2019年第1期72-76,共5页
Journal Of Clinical Nephrology
基金
北京市科委计划项目(No.Z151100003915098)
关键词
慢性肾脏病
胱抑素C
预后
危险因素
Chronic kidney disease
Cystatin C
Prognosis
Risk factor
