摘要
目的 :将牛腱胶原膜加工制备成双抗胶原膜应用于临床GTR治疗 ,观察比较牛腱胶原膜和双抗胶原膜的临床疗效。方法 :随机分组 ,分别应用双抗胶原膜和牛腱胶原膜对 2 4例牙周炎患者 ,共 2 6颗患牙、31处骨病损进行GTR治疗 ,术后 6个月复查检测临床指标及Digora分析平行定位X线片骨密度的改变。结果 :实验组 (双抗胶原膜组 )临床附着获得平均为 (2 .2 16± 1.184 )mm ;对照组 (牛腱胶原膜组 )平均为 (1.316± 0 .719)mm(t testP <0 .0 5 ) ;Digora分析显示GTR术后实验组骨密度增加值平均为 (2 5 .71± 12 .2 5 ) ,对照组为 (11.2 9± 12 .73) (t testP <0 .0 5 )。结论 :临床应用双抗胶原膜比应用牛腱胶原膜能获得更多的生理性新附着 ,更大程度地促进牙槽骨生理性再生。
Objective: To compare the clinical effects of Bi anti collagen membrane in GTR with that of the original collagen membrane. Methods: Twenty four patients (thirty one defects), were treated with Bi anti collagen membranes or the original collagen membranes randomly. Six months after operation, changes of clinical parameters and the density of alveolar bone around the involved teeth in X ray were observed to evaluate the difference of clinical effects between two kinds of membranes. Results: The gain of clinical attachment in test group (using Bi anti collagen membranes)[(2.216±1.184)mm] was compared with that in control group (using the original collagen membranes) [(1.316±0.719)mm] after six months (P<0.05). Digora image processing showed more obvious regeneration of alveolar bone in test group (test group: 25.71±12.25; control group: 11.29±12.73,P<0.05). Conclusion: Bi anti collagen membranes come to better the clinical effects of GTR to some extent. It is of clinical significance to modify the original collagen membrane.
出处
《武汉大学学报（医学版）》
CAS
2003年第2期180-182,188,共4页
Medical Journal of Wuhan University
关键词
引导组织再生
胶原膜
牙周炎
guided tissue regeneration
collagen membrane
periodontitis
