摘要
DNA双链断裂(DSB)的定量分析是高传能线密度辐射生物学效应机理研究的重要手段.从实际应用出发,推导了一个新的计算公式———平均分子量法.该法不探究DSB片段的具体分布模式,实际操作中却又包含了片段的含量和分布;而且形式简单、操作简便,尤其适合于荧光扫描数据.
Quantitive analysis of DNA doublestrand break (DSB) is of importance for studying on the mechanisms of radiobiological effects induced by high linear energy transfer(LET) irradiation. For the practical use, one new calculating formula named the method of average molecular weight is deducted. In this method, the factual distribution of DSB fragments is not considered, but actually, the content and distribution of DSB fragments are included. Totally, this method is simple in shape and easy to use, especially for the data obtained from fluorescence scanning.
出处
《原子核物理评论》
CAS
CSCD
北大核心
2003年第1期52-54,共3页
Nuclear Physics Review
基金
中国科学院西部之光课题(XB980604)~~
