摘要
目的 :调查人类巨细胞病毒 (HCMV)活动性感染人群的分布及流行病学特征 ,为预防和诊治HCMV活动性感染提供证据。方法 :用ELISA法测定血清中HCMV活动性感染的特异性抗体HCMV -IgM ,并对HCMV -IgM检测人群进行分析。结果 :90例健康人群血清HCMV活动性感染率为 0 ;5 315例孕妇血清HCMV -IgM检测中有 30 3例为阳性 ,HCMV活动性感染率平均为 5 .70 % ,但孕妇HCMV活动性感染率有逐年下降趋势 ;5 1例不明原因的黄疸患者、16例器官移植患者、3例发热待查患者 ,HCMV活动性感染率分别为 3.92 %、12 .5 %、0 %。结论 :移植患者、孕妇、不明原因的黄疸患者易受HCMV活动性感染 ,临床上应将其作为高危人群常规筛查HCMV -IgM。
Objective: To investigate the distribution and epidemiological feature in the patients of active human cytomegalovirus (HCMV) infection,and to provide evidence in active HCMV infection for prevention and clinical diagnosis and therapy. Methods: Determined and analysed serum specific antibody HCMV-IgM of active HCMV infection in patients by enzyme-linked immunoadsordent assay (ELISA). Results: The positive rates of HCMV-IgM were 0% in a control group of 90.The mean infection rates of active HCMV were 5.70%,3.92%,12.5% and 0% of pregnant women of 5315 and unknown case of icteric patients of 51 and transplant recipient of 16 and unknown case of fever patients.But the infection rates of active HCMV were in descending tendency in pregnant women year after year. Conclusion: The transplant recipient,the pregnant woman,and unknown case of icteric patients were active high risk HCMV infection group,and HCMV-IgM of routine screening plays an important role in clinical diagnosis and treatment.
出处
《重庆医科大学学报》
CAS
CSCD
2003年第2期195-197,共3页
Journal of Chongqing Medical University
