摘要
目的 :探究高通量血液透析对尿毒症患者不宁腿综合征及钙磷代谢的影响,为患者的治疗提供参考。方法 :选择我院2016年5月~2018年5月间收治尿毒症患者300例作为本次研究对象,按照患者治疗方式的不同将其分为观察组和对照组各150例,观察组患者采取高通量透析治疗,对照组患者采用低通量透析治疗,分析两组患者不宁腿综合征评分比较以及钙磷代谢情况。结果 :观察组患者治疗前不宁腿综合征评分与对照组比较差异无统计学意义,经过治疗后,观察组患者不宁腿综合征评分明显低于对照组,两组比较差异有统计学意义;观察组患者治疗前Ga、P、PTH以及AKP水平与对照组比较差异无统计学意义,经过治疗后,观察组患者P、PTH以及AKP水平明显低于对照组,两组比较差异有统计学意义,而Ga水平与对照组比较差异无统计学意义;观察组患者治疗前Scr、BUN、β2-MG以及sTfR水平与对照组比较差异无统计学意义,经过治疗后,观察组患者β2-MG以及sTfR水平明显降低,两组比较差异有统计学意义,而Scr以及BUN水平与对照组比较差异无统计学意义。结论 :高通量血液透析有助于改善尿毒症不宁腿综合征患者病情以及钙磷代谢异常,值得在临床治疗中广泛推广。
Objective To investigate the effects of high-flux hemodialysis on restless legs syndrome and calcium and phosphorus metabolism in uremic patients,and to provide reference for the treatment of patients.Methods 300 patients with uremia admitted to our hospital from May 2016 to May 2018 were selected as the subjects of this study.According to the different treatment methods,150 patients were divided into observation group and control group.The observation group patients took high.Flux dialysis treatment,the control group of patients with low-flux dialysis treatment,analysis of the two groups of patients with restless legs syndrome scores and calcium and phosphorus metabolism.Results There was no significant difference in the scores of restless legs syndrome between the observation group and the control group.After treatment,the scores of restless legs syndrome in the observation group were significantly lower than those in the control group.Statistical significance;the levels of Ga,P,PTH and AKP in the observation group were not significantly different from those in the control group.After treatment,the P,PTH and AKP levels in the observation group were observed.There was significant difference between the two groups,but there was no significant difference between the two groups.The patients in the observation group were treated with Scr,BUN andβ2-MG.There was no significant difference between the sTfR level and the control group.After treatment,the levels ofβ2-MG and s Tf R in the observation group were significantly lower.The difference between the two groups was statistically significant,while Scr There was no significant difference between the BUN level and the control group.Conclusion High-flux hemodialysis can improve the condition of patients with uremia and restless legs syndrome and abnormal calcium and phosphorus metabolism,which is worthy of widespread promotion in clinical treatment.
作者
罗进辉
张慧
童运涛
杨柳
Luo Jin-hui;Zhang Hui;Tong Yun-tao;Yang Liu(Hubei Wuhan Hankou Hospital Nephrology,Wuhan 430012,China)
出处
《湖南师范大学学报（医学版）》
2019年第3期82-84,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
高通量血液透析
尿毒症
不宁腿综合征
钙磷代谢
high-throughput hemodialysis
uremia
restless legs syndrome
calcium and phosphorus metabolism
