摘要
目的 :研究腹膜淋巴结转移癌诱发的肠梗阻应用肠系膜上动脉(SMA)灌注化疗的临床疗效。方法 :选取我院2015年1月1日～2016年12月1日收治的腹膜淋巴结转移癌诱发的肠梗阻患者94例,按照随机数表法分为两组,每组47例,对照组患者给予肠梗阻常规治疗,观察组患者给予SMA灌注化疗,比较两组患者治疗后临床疗效,临床症状缓解时间、不良反应发生率以及生存时间。结果 :观察组患者治疗后总有效率明显高于对照组(91.49%vs 76.60%),比较有统计学意义;观察组患者恢复排气时间、恢复排便时间以及腹胀、腹痛缓解时间均明显短于对照组,观察组患者肠道通畅维持时间明显长于对照组,比较有统计学意义;观察组患者不良反应发生率明显低于对照组(8.51%vs 23.40%),差异显著;观察组患者治疗后生存时间(5.28±1.16)个月明显长于对照组(2.15±0.86)个月,差异有统计学意义。结论 :给予由于腹膜淋巴结转移癌诱发的肠梗阻患者SMA灌注化疗可促进患者的恢复,缩短患者临床症状缓解时间,临床疗效显著,值得临床推广应用。
Objective To study the superior mesenteric artery(SMA) in intestinal obstruction caused by peritoneal lymph node metastasis. Methods 94 cases of intestinal obstruction induced by peritoneal lymph node metastasis cancer who received treatment from January 1, 2015 to December 1, 2016 in our hospital, randomly divided into two groups, each group of 47 cases, the patients in the control group were given routine treatment of intestinal obstruction, while the patients in the observation group were given SMA perfusion chemotherapy, then the clinical efficacy, clinical symptom remission time, adverse reaction rate and survival time were compared between the two groups. Results The total effective rate of the observation group was significantly higher than that of the control group(91.49% vs 76.60%), which was statistically significant;the recovery time, recovery time and abdominal distension and abdominal pain relief time of the observation group were significantly shorter than those of the control group, while the observation group was longer than that of the control group, and the difference was statistically significant;the incidence of adverse reactions in the observation group was significantly lower than that in the control group(8.51% vs 23.40%), the difference was significant;the survival time(5.28±1.16) months after treatment in the observation group was significantly longer than that of the control group(2.15±0.86) months, and the difference was statistically significant. ConclusionSMA perfusion chemotherapy for patients with intestinal obstruction caused by peritoneal lymph node metastasis can promote the recovery of patients and shorten the remission time of clinical symptoms, which is worthy of clinical application.
作者
马旭
李晓慧
艾旭
龙舟
Ma Xu;Li Xiao-hui;Ai Xu;Long Zhou(Jingmen First People’s Hospital, Jingmen 448001, China)
出处
《湖南师范大学学报（医学版）》
2018年第6期144-146,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
腹膜淋巴结转移癌
肠梗阻
肠系膜上动脉
灌注化疗
peritoneal lymph node metastases
intestinal obstruction
mesenteric artery
perfusion chemotherapy
