摘要
目的 :探讨髋关节置换术后血栓形成与凝血因子之间的关系,为临床或科研研究血栓与凝血因子相互之间的关系提供一些科学依据。方法 :选取2012年2月~2014年2月在我院行髋关节置换术的80例患者,其中其中40例为未发生血栓的患者为对照组,40例为发生血栓的患者为观察组。采用回顾性分析研究方法,总结两组患者手术前后血清中相关凝血因子的变化及凝血因子与血栓之间的关系,及凝血因子对机体产生的影响(C-反应蛋白的变化)。最后统计分析。结果 :两组治疗前凝血因子(Ⅰ、Ⅱ、Ⅶ、Ⅹ、Ⅻ)相互之间无明显差异;但是两组治疗后,观察组凝血因子(Ⅰ、Ⅱ、Ⅶ、Ⅹ、Ⅻ)的含量普遍高于对照组;对照组治疗前后凝血因子(Ⅰ、Ⅱ、Ⅶ、Ⅹ、Ⅻ)相互之间的无明显差异;而观察组治疗前后凝血因子(Ⅰ、Ⅱ、Ⅶ、Ⅹ、Ⅻ)相互之间的差异明显。两组治疗前患者血清C-反应蛋白量之间无明显差异;两组治疗后,观察组患者血清C-反应蛋白量明显高于对照组;两组治疗前后患者血清C-反应蛋白量之间的差异明显。结论 :行髋关节置换术后血栓形成术的患者,术后创伤性大,与凝血因子的变化密切相关。
Objective to investigate the thrombosis after hip replacement and blood coagulation factor, the relationship between the clinical or scientific research thrombus and blood coagulation factor to provide some scientific basis for the relationship between each other. Methods from February 2012 to February 2014 in our hospital 80 cases of hip replacement patients, 40 cases of thrombosis in patients as control group, 40 cases of blood clots for observation group of patients. By the method of retrospective analysis and summary of two groups of patients before and after surgery related clotting factor changes in serum and blood coagulation factor and the relationship between the thrombus, and blood coagulation factor of influence on the body(C-reactive protein change). The statistical analysis. Results the two groups before treatment clotting factor(Ⅰ Ⅱ Ⅶ Ⅹ Ⅻ) the difference between each other; But the two groups after treatment, the observation group of clotting factor(Ⅰ Ⅱ Ⅶ Ⅹ Ⅻ) content is generally higher than that of control group, two groups of blood coagulation factor(Ⅰ Ⅱ Ⅶ Ⅹ Ⅻ) the difference between each other; The control blood coagulation factor before and after the treatment(Ⅰ Ⅱ Ⅶ Ⅹ Ⅻ) between difference; Blood coagulation factor before and after the treatment and observation group(Ⅰ Ⅱ Ⅶ Ⅹ Ⅻ) the difference between each other. The two groups before treatment between patients serum C-reactive protein quantity difference; The two groups after treatment, observation group of patients serum C-reactive protein is significantly higher than the control group, two groups of patients after treatment the difference between the amount of serum C-reactive protein; The control group patients before and after treatment the difference between the amount of serum C-reactive protein;Observation group patients before and after treatment the difference between the amount of serum C-reactive protein. Conclusion thrombosis after hip replacement surgery patients, postoperative trau
出处
《湖南师范大学学报（医学版）》
2015年第5期77-79,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
髋关节置换术
血栓
凝血因子
相互关系
Hip replacement
Blood clots
Clotting factor
The relationship between them
