摘要
目的:探讨坦索罗辛0.2mg联合非那雄胺5mg对老年前列腺增生症患者的焦虑及睡眠的影响。方法:观察35例老年前列腺增生症患者。年龄56-84岁,平均70岁。入选的35例BPH患者,口服坦索罗辛0.2mg加非那雄胺5mg,疗程三个月,观察患者服药前和服药后的国际前列腺症状评分表IPSS、焦虑程度SAS、阿森斯失眠量表AIS及生活质量评分表QOLS。结果:服药前有19例(54.3%)伴焦虑,服药后10例(28.57%)伴焦虑;服药前16例(45.71%)伴失眠,服药后8例(22.86%)伴失眠。服药前、服药后患者焦虑、睡眠障碍发生率比较,差异,有统计学意义。服药前后IPSS从25.00±3.93到15.85±3.51、SAS从38.06±6.10到26.50±5.72,AIS从10.60±5.06到5.00±4.22,QOLS从3.95±0.76到3.10±0.641,治疗前后比较有统计学意义。结论:坦索罗辛联合非那雄胺治疗前列腺患者能够缓解下尿路症状,改善老年前列腺增生症患者的焦虑、睡眠及生活质量。
Objective To evaluate the effect of tamsulosin (0.2mg) and finasteride (0.5mg) on anxiety and sleeping for benign prostate hypertrophy patients . Metheods Observed 35 benign prostate hypertrophy patients Patients were treated with tamsulosin 0.2mg,qd and combined with finasteride 0.2mg,qd for 3 months . IPSS,SAS, AIS and QOLS were measured before and after the treatment. Results Before taking the medicine, 19 cases (54.3%) with anxiety, after the treatment,10cases (28.57%) with anxiety ; Before taking the medicine16cases (45.71%) with insomnia , after the treatment, 16 cases (45.71%) with insomnia. There was significant difference between before the treatment and after the treatment. P<0.05 .Before the treatment ,average IPSS 25.00±3.93, av-erage SAS 38.06±6.10, average AIS 10.60±5.06, and average QOLS 3.95±0.76;After 3 months treatment , average IPSS 15.85±3.51. average SAS 26.50±5.72, average AIS 5.00±4.22 and average QOLS 3.10±0.641. There was significant difference between before the treatment and after the treatment. P<0.05. Conclusion Treatment of benign prostatic hyperplasia (BPH) with tamsulosin hydrochloride Sustained-Release Capsules combined with fi-nasteride Tablets could relieve lower urinary tract symptoms, improve anxiety, sleeping and the quality of life
出处
《湖南师范大学学报（医学版）》
2013年第2期58-60,共3页
Journal of Hunan Normal University(Medical Sciences)
