摘要
目的探讨急性脑梗死患者血脂、血尿酸、纤维蛋白原和C反应蛋白的变化及意义。方法检测并进行比较120例急性脑梗死患者与110例健康体检者血脂、血糖、血尿酸;120例急性脑梗死患者依据血尿酸水平,分为正常血尿酸组与高血尿酸组,比较2组甘油三酯(TG)、总胆同醇(TcH)、高密度脂蛋白胆固醇(HDL-c)、低密度脂蛋白胆同醇(LDL-c)、血尿酸(μA)、纤维蛋白原(Fib)、血糖(GLU)、C反应蛋白(CRP)。结果脑梗死组μA、GLU水平较健康对照组升高,差异有统计学意义(t=4.736,P=0.000;t=5.99,P=0.000);脑梗死组依据尿酸进行分组,高尿酸组纤维蛋白原(Fib)差异有统计学意义(t=2.279,P=0.025);血甘油三酯(TG)、总胆固醇(TcH)、高密度脂蛋白胆固醇(HDL-c)、低密度脂蛋白胆同醇(LDL-c)、血糖(GLU)、C反应蛋白(CRP)差异无统计学意义(P>0.05)。结论血尿酸是急性脑梗死重要危险因素之一,血尿酸水平与纤维蛋白原呈正相关,可能参与凝血功能改变。
Objective To research on the significance and change of blood lipid,blood uric acid,fibrinogen and C-reactive protein in acute cerebral infarction patients.Methods The levels of CHO,blood sugar and uric acid in 120 cases with acute cerebral infarction and 110 healthy persons were compared.On the basis of the level of serum uric acid,120 patients with acute cerebral infarction divided into normal uric acid group and hyperuricemia group.The blood levels of alcohol triglycerides(TG),total cholesterol(TCH),high-density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),blood uric acid(UA),fibrinogen(Fib),and glucose(GLU),C-reactive protein(CRP)were compared and analyzed.Results The levels of UA,Fib,GLU in acute cerebral infarction patients increased obviously compared with normal group(t=4.736,P=0.000;t=5.99,P=0.000).According to the level of blood uric acid in the acute cerebral infarction group,the Fib level increased significantly between hyperuricemia group and normal uric acid group(t=2.279,P=0.025).But the levels of TG,TCH,HDL-C,LDL-C,GLU,CRP had no statistical significant between the two groups(P>0.05).Conclusion The level of blood uric acid is one of the important risk factors of acute cerebral infarction.There is a correlation between the level of uric acid and fibrinogen,and it is more likely to participate in coagulation function.
出处
《中国实用神经疾病杂志》
2014年第21期17-18,共2页
Chinese Journal of Practical Nervous Diseases
关键词
脑梗死
血尿酸
纤维蛋白原
C反应蛋白
Cerebral infarction
Blood uric acid
Fibrinogen
C-reactive protein
