摘要
目的研究不同剂量辛伐他汀对缺血性脑血管患者脑血管储备能力的影响。方法将90例缺血性脑血管患者分为常规组、强化组和对照组。对照组患者口服拜阿司匹林,对症治疗;常规组患者服用常规剂量辛伐他汀治疗;强化组服用强化剂量辛伐他汀治疗。检测比较患者治疗前后的脑血管储备能力。结果治疗6个月后,常规组屏气指数为1.21±0.13,脑血管储备能力为30.44±5.09;强化组屏气指数为1.54±0.11,脑血管储备能力为36.14±5.13;对照组的屏气指数为0.95±0.11,脑血管储备能力为21.42±5.20。3组患者的屏气指数和脑血管储备能力较治疗前均有一定程度增加,但强化组增加的幅度最明显。结论强化剂量的辛伐他汀对患者CVR有较好疗效。
Objective To investigate the effects of different does simvastatin on the cerebrovascular reserve capacity (CVR) of patients with ischemic cerebrovascular disease·Methods 90 patients with ischemic cerebrovascular disease were di-vided into the control group (treated with oral bayaspirin) ,convention group (treated with conventional does simvastatin ) and strengthened group (treated with strengthened does simvastatin)· The cerebrovascular reserve capacities of three groups were compared·Results After being treated for 6 months ,the breath-holding index and CVR were 1·21 ± 0·13 and 30·44 ± 5·09 in the convention group ,1·54 ± 0·11 and 36·14 ± 5·13 in the strengthened group ,0·95 ± 0·11 and 21·42 ± 5·20 in the control group ,respectively· Compared with pretreatment ,the breath-holding index and CVR of three groups had certain degree of in-crease ,especially in the strengthened group·Conclusion Strengthened does simvastatin has better effect on the CVR of pa-tients w ith ischemic cerebrovascular disease.
出处
《中国实用神经疾病杂志》
2014年第21期8-10,共3页
Chinese Journal of Practical Nervous Diseases
关键词
储备能力
辛伐他汀
缺血性脑血管
Cerebrovascular reserve capacity
Simvastatin
Ischemic cerebrovascular disease
