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非布司他治疗痛风患者对血脂代谢影响 被引量:3

Effect of Feiburestar on Blood Lipid Metabolism in patients with Gout
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摘要 目的:观察非布司他治疗痛风患者对血脂代谢影响。方法:随机选取2017年3月-2018年3月至我院进行痛风治疗的患者70例,分为对照组和观察组各35例。对照组给予别嘌醇片,日2次,口服。观察组给予非布司他片40mg,日1次,口服。观察两组患者治疗前后血尿酸(UA)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、血清总胆固醇(TC)水平。结果:两组患者治疗后与治疗前UA相比均明显降低,但观察组UA水平明显低于对照组。观察组患者治疗后TG、LDL、TC水平均明显低于对照组,两组患者HDL水平无明显差异(p>0.05),从组间比较来看,观察组患者治疗后TG、LDL、HDL、TC水平与治疗前相比均明显改善(p<0.05),对照组患者治疗后HDL水平明显高于治疗前,但TG、LDL、TC水平无明显变化(p>0.05)。观察组总计发生4例不良反应,发生率为11.43%,明显低于对照组12例,34.29%。结论:痛风患者采用非布司他治疗,可以有效改善患者血脂水平,降低患者不良反应的发生率。
作者 陈艳 高利霞 钟彩玲 吴小清 钟昊 观美华 Chen Yan;Gao Lixia;Zhong Cailing;Wu Xiaoqing
出处 《黑龙江中医药》 2018年第6期101-102,共2页 Heilongjiang Journal of Traditional Chinese Medicine
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