摘要
目的观察经鼻持续正压通气（CPAP）辅助治疗毛细支气管炎合并呼吸衰竭患儿的临床效果。方法选取本院儿科自2014年112月收治的98例毛细支气管炎合并呼吸衰竭患儿,根据入院顺序分为观察组和对照组各49例,两组患儿均给予解痉平喘、吸痰、抗感染、纠正电解质紊乱等治疗,观察组同时给予CPAP治疗,对照组则给予经鼻导管吸氧治疗,比较两组患儿治疗后的血气指标、临床症状缓解时间及治疗效果。结果治疗后12 h、24 h,两组患儿的心率（HR）、血液酸碱度（p H）、动脉血二氧化碳分压（Pa CO2）、血氧饱和度（Sp O2）、动脉血氧分压（Pa O2）较治疗前均明显好转,差异均有统计学意义（P<0.05）,且观察组的上述指标均优于对照组,差异均有统计学意义（P<0.05）;观察组紫绀消失时间、喘憋消失时间、心率恢复时间、哮鸣音消失时间和住院时间均明显短于对照组,差异均有统计学意义（P<0.05）;治疗3 d后观察组的显效率为69.39%,明显高于对照组的48.98%,差异有统计学意义（P<0.05）。结论采用经鼻持续正压通气辅助治疗毛细支气管炎合并呼吸衰竭患儿能够缩短治疗时间,缓解患儿的临床症状,提高临床治疗效果。
Objective To observe the clinical effect of nasal continuous positive airway pressure（CPAP） in the treatment of children with bronchiolitis complicated by respiratory failure. Methods A total of 98 children with bronchiolitis complicated by respiratory failure treated in our hospital from January 2014 to December 2014 were selected, which were divided into observation group and control group according to the order of admission, each with 49 children. The two groups were both given antispasmodic, suctioning, anti-infective treatment, as well as correction of electrolyte imbalance. The observation group received CPAP therapy, while the control group was treated with nasal cannula oxygen therapy. Blood gas indicators, clinical symptoms and treatment time were compared between the two groups.Results 12 h, 24 h after treatment, heart rate（HR）, blood acidity（p H）, arterial carbon dioxide pressure（Pa CO2）, oxygen saturation（Sp O2）, arterial oxygen tension（Pa O2） in the two groups were all significantly improved compared with those before treatment（P<0.05）, and the indexes of the observation group were significantly better than those of the control group（P<0.05）. The cyanosis disappeared time, shortness of breath disappeared time, heart rate recovery time,wheezing disappeared time and length of hospital stay were significantly shorter in the observation group than the control group（P<0.05）. The effective rate was 69.39% in the observation group 3 d after treatment, significantly higher than48.98% in the control group（P<0.05）. Conclusion Using nasal continuous positive airway pressure for adjunctive therapy in children with bronchiolitis complicated by respiratory failure can shorten the treatment time, relieve symptoms,and improve clinical outcomes.
出处
《海南医学》
CAS
2016年第1期59-61,共3页
Hainan Medical Journal
基金
陕西省科学技术厅资助课题[编号:2005K12-G5(10)]
关键词
经鼻持续正压通气
毛细支气管炎
呼吸衰竭
临床效果
Nasal continuous positive pressure ventilation
Capillary bronchitis
Respiratory failure
Clinical effect
