摘要
目的:探讨硫酸镁联合硝苯地平治疗妊娠高血压的临床效果。方法:选取2022年6月—2023年6月东明县妇幼保健院收治的妊娠高血压患者130例作为研究对象,随机分为对照组与观察组,各65例。对照组给予硫酸镁治疗,观察组在对照组基础上联合硝苯地平治疗。对比两组血压水平、治疗效果、不良事件、血黏度、脐动脉阻力指数及不良反应。结果:治疗后,两组收缩压、舒张压水平均低于治疗前,且观察组低于对照组(P<0.05)。观察组治疗总有效率高于对照组,不良事件总发生率低于对照组(P<0.05)。治疗后,两组血黏度、脐动脉阻力指数均低于治疗前,且观察组低于对照组(P<0.05)。观察组不良反应总发生率低于对照组(P=0.033)。结论:硫酸镁联合硝苯地平治疗妊娠高血压的临床效果显著,能够控制孕妇血压,降低血黏度、脐动脉阻力指数及不良反应发生率,改善妊娠结局。
Objective:To explore the clinical effect of magnesium sulfate combined with nifedipine in the treatment of pregnancy hypertension.Methods:A total of one hundred and thirty patients with gestational hypertension admitted to Dongming County Maternal and Child Health Hospital from June 2022 to June 2023 were selected as the study objects and randomly divided into control group and observation group,with sixty-five cases in each group.The control group was treated with magnesium sulfate,and the observation group was treated with nifedipine based on the control group.Blood pressure level,therapeutic effect,adverse events,blood viscosity,umbilical artery resistance index and adverse reactions were compared between the two groups.Results:After treatment,the levels of systolic and diastolic blood pressure in both groups were lower than before treatment,and the observation group was lower than the control group(P<0.05);the total effective rate of treatment in observation group was higher than that in control group,and the total incidence of adverse events was lower than that in control group(P<0.05);after treatment,blood viscosity and umbilical artery resistance index in both groups were lower than before treatment,and observation group was lower than control group(P<0.05);the total incidence of adverse reactions in observation group was lower than that in control group(P=0.033).Conclusion:Magnesium sulfate combined with nifedipine has significant clinical effect in the treatment of pregnancy hypertension,which can control pregnant women's blood pressure,reduce blood viscosity,umbilical artery resistance index and incidence of adverse reactions,and improve pregnancy outcome.
作者
乔培灵
Qiao Peiling(Dongming County Maternal and Child Health Hospital,Heze 274500,Shandong Province,China)
出处
《中国社区医师》
2024年第32期62-64,共3页
Chinese Community Doctors
关键词
妊娠高血压
硫酸镁
硝苯地平
Pregnancy hypertension
Magnesium sulfate
Nifedipine
