摘要
目的:观察婴儿退黄包药浴早期干预对新生儿高胆红素血症(NHB)的预防效果。方法:选取2023年4—9月于东莞市黄江医院出生的新生儿99例为研究对象,依照随机数字表法分成对照组(49例)和中药组(50例)。对照组采用常规新生儿护理干预,中药组在对照组基础上采用婴儿退黄包药浴早期干预。比较两组NHB发病率,血清总胆红素(TBiL)、结合胆红素(DBiL)、总胆汁酸(TBA)水平及黄疸持续时间。结果:中药组NHB发病率低于对照组(P=0.003)。干预前,两组TBiL、DBiL、TBA水平比较,无统计学差异(P>0.05);干预后,两组TBiL、DBiL、TBA水平升高,但中药组低于对照组(P<0.001);中药组黄疸持续时间较对照组短(P<0.05)。结论:婴儿退黄包药浴早期干预对新生儿NHB预防效果较好,能有效控制血清TBiL、DBiL、TBA水平,缩短NHB持续时间。
Objective:To observe the effect of early intervention of infant Tuihuangbao medicated bath on the prevention of neonatal hyperbilirubinemia(NHB).Methods:Ninety-nine neonates born in Dongguan Huangjiang Hospital from April to September 2023 were selected as study subjects and divided into the control group(forty-nine cases)and the traditional Chinese medicine group(fifty cases)according to the method of randomized numerical table.The control group used conventional neonatal care interventions,and the traditional Chinese medicine group used early intervention based on the control group with the infant Tuihuangbao medicated bath.The incidence of NHB,serum total bilirubin(TBiL),conjugated bilirubin(DBiL),total bile acids(TBA)levels and duration of jaundice were compared between the two groups.Results:The incidence of NHB in the traditional Chinese medicine group was lower than that in the control group(P=0.003);before intervention,there was no statistical difference in the levels of TBiL,DBiL,and TBA between the two groups(P>0.05);after intervention,the levels of TBiL,DBiL,and TBA increased in the two groups,but they were lower in the traditional Chinese medicine group than in the control group(P<0.001);the duration of jaundice in the traditional Chinese medicine group was shorter than that in the control group(P<0.05).Conclusion:Early intervention of infant Tuihuangbao medicated bath is more effective in the prevention of NHB in newborns,which can effectively control serum TBiL,DBiL and TBA levels and shorten the duration of NHB.
作者
黎沛娴
廖连芳
周茜
胡晓怡
袁海英
Li Peixian;Liao Lianfang;Zhou Xi;Hu Xiaoyi;Yuan Haiying(Dongguan Huangjiang Hospital,Dongguan 523700,Guangdong Province,China)
出处
《中外医药研究》
2024年第30期115-117,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
